Evaluation of 3DCRT Versus IGRT and Analysis of Early Response in Head and Neck Cancer.
NCT ID: NCT01124409
Last Updated: 2011-06-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE3
41 participants
INTERVENTIONAL
2009-12-31
2011-08-31
Brief Summary
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Detailed Description
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1. To assess the patient's radiation dose planning for GTV, CTV and PTV for primary and nodal regions and derive comparison between IGRT and 3D-CRT.
2. To assess the dosimetric variation in different phases of adaptive RT due to changes in tumor shape and volume during the course of entire treatment in IGRT arm in head and neck cancer patients.
3. To evaluate the optimal setup correction methodology using planar (EPID) and volumetric images (CBCT) in HNSCC between 3D-CRT and IGRT treatment delivery respectively.
4. To compare the early tumour response and acute and chronic radiation morbidities between IGRT and 3D-CRT.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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3DCRT with EPID
this patients randomised to this arm will be planned by 3DCRT and during treatment setup error will be identified and corrected by weekly EPID if error \>3mm.Weekly CBCT will be done for this arm to note the setup error but will not be corrected.
EPID Verification
Set up error verification and correction by EPID
IGRT with CBCT
The patients randomised to this arm will be planned by 3DCRT and set up error during RT will be verified by CBCT and error corrected if \>3mm.Weekly EPID will be done for setup error documentation but no correction based on EPID in this arm.
CBCT verification
Setup error verification and correction by CBCT
Interventions
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EPID Verification
Set up error verification and correction by EPID
CBCT verification
Setup error verification and correction by CBCT
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Informed Consent
* KPS score \> 70
Exclusion Criteria
* Not ready for follow up
* Previous cancer directed therapy
18 Years
65 Years
ALL
No
Sponsors
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All India Institute of Medical Sciences
OTHER
Responsible Party
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ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Principal Investigators
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BIDHU K MOHANTI, MD
Role: STUDY_CHAIR
All India Institute of Medical Sciences
Locations
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All India Institute of Medical Sciences
New Delhi, New Delhi, India
Countries
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Other Identifiers
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3DIGHNC
Identifier Type: -
Identifier Source: org_study_id
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