The Relationship Between Microbiota and Coronary Ectasia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-11-03

Study Completion Date

2021-06-18

Brief Summary

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Introduction: It is now known that the microbiota is far beyond the microbial communities living in certain parts of our body and functions like a metabolic organ. In addition, the microbiota, through its metabolites, is involved in the pathophysiology or progression of a wide range of diseases, from atherosclerotic diseases to metabolic diseases and even neurological diseases. Among these metabolites, trimethylamine n-oxide metabolite has been shown to be particularly effective on atherosclerotic heart diseases.

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Detailed Description

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Conditions

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Coronary Ectasia Microbial Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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coronary ectasia cohort

Patients with coronary ectasia detected on coronary angiography and without any exclusion criteria were included.

Taking blood for kit study

Intervention Type DIAGNOSTIC_TEST

Taking blood for kit study (Elisa kit)

normal coronary cohort

Patients who underwent coronary angiography and did not have any of the exclusion criteria

Taking blood for kit study

Intervention Type DIAGNOSTIC_TEST

Taking blood for kit study (Elisa kit)

Interventions

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Taking blood for kit study

Taking blood for kit study (Elisa kit)

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* over 18 years old
* not having occlusive coronary artery disease
* having coronary ectasia

Exclusion Criteria

* patients with chronic kidney disease,
* revascularized coronary artery disease,
* previously documented critical coronary stenosis,
* acute or chronic inflammatory disease,
* rheumatologic disease,
* known active malignant disease,
* heart failure,
* moderate-to-severe valvular pathology
* patients who were on any steroid or immunosuppressive therapy

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes