Disparities in Myocardial Infarction Remodeling According to Gender

NCT ID: NCT06343844

Last Updated: 2024-07-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

1650 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-07-15

Study Completion Date

2040-09-01

Brief Summary

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Following myocardial infarction, female individuals demonstrate a poorer prognosis, characterized by elevated rates of mortality and heart failure. A primary hypothesis suggests unfavorable cardiac remodeling in women. This remodeling, defined as alterations in cardiac size and shape post-infarction, necessitates repeated non-invasive imaging for study.

Detailed Description

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Conditions

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Myocardial Infarction Ventricular Remodeling

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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case control registry

left ventricular remodeling measurement with cardiac echography

Group Type OTHER

cardiac imaging to assess left ventricular volumes and function

Intervention Type DIAGNOSTIC_TEST

non-invasive cardiac imaging (echocardiography and MRI)

Interventions

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cardiac imaging to assess left ventricular volumes and function

non-invasive cardiac imaging (echocardiography and MRI)

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age \> 18 years
* First myocardial infarction with ST-segment elevation during the hospital phase
* Coronary angiography performed within 72 hours of the infarction
* Inclusion in the RIMA registry
* Patient affiliated or beneficiary of a social security scheme; Signature of informed consent

Exclusion Criteria

* Patients already enrolled in the study
* Poor understanding of the French language
* Pregnant, breastfeeding, or postpartum women
* Individuals deprived of liberty by judicial or administrative decision; Individuals receiving psychiatric care under coercion
* Individuals subject to a legal protection measure; Individuals incapable of giving consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Angers

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University Hospital, Angers

Angers, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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LOIC BIERE, PHD

Role: CONTACT

02 41 35 36 37 ext. +33

VIVIANE CASSISA

Role: CONTACT

02 41 35 36 37 ext. +33

Facility Contacts

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LOIC BIERE, PHD

Role: primary

0241353637 ext. +33

Other Identifiers

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49RC23_0070

Identifier Type: -

Identifier Source: org_study_id

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