A Multicenter, Prospective Cohort Study of Preserved Ratio Impaired Spirometry(PRISm) in a Population
NCT ID: NCT06340295
Last Updated: 2024-04-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
2000 participants
OBSERVATIONAL
2023-09-01
2026-05-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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new-onset COPD group
FEV1/FVC\<0.7 after bronchodilator inhalation during 3 years of follow-up
Continuous PRISm group
After bronchodilator inhalation, FEV1/FVC≥70% and the percentage of FEV1pred%\<80% during 3 years of follow-up
PRISm to normal group
After bronchodilator inhalation, FEV1/FVC≥0.7 and FEV1pred% ≥80% during 3 years of follow-up
Interventions
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
2\) Have undergone lobectomy and/or lung transplantation; 3) complicated with serious underlying diseases (including serious mental illness, mental retardation, neurological disease, malignant tumor, chronic liver disease, heart failure, autoimmune disease, chronic kidney disease); 4) accompanied by severe pleural disease and/or lesions of the sternum or ribs; 5) Have active tuberculosis or are receiving anti-tuberculosis treatment; 6) Pregnancy or lactation; 7) Can not be followed up for a long time or poor compliance;
20 Years
75 Years
ALL
No
Sponsors
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Shanxi Bethune Hospital
OTHER
First Affiliated Hospital Xi'an Jiaotong University
OTHER
Tianjin Medical University General Hospital
OTHER
The First Hospital of Qinhuangdao
OTHER_GOV
Shandong Provincial Hospital
OTHER_GOV
Second Hospital of Jilin University
OTHER
People's Hospital of Xinjiang Uygur Autonomous Region
OTHER
MinDong Hospital of Ningde City
UNKNOWN
Peking University First Hospital
OTHER
Responsible Party
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Principal Investigators
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Guangfa Wang, MD.
Role: STUDY_CHAIR
Peking University First Hospital
Locations
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Peking University First Hospital
Beijing, Beijing Municipality, China
Peking University First Hospital
Beijing, Beijing Municipality, China
The First Hospital of Qinhuangdao
Qinhuangdao, Hebei, China
Tianjin Medical University General Hospital
Tianjin, Tianjin Municipality, China
Shandong Provincial Hospital Affiliated to Shandong University
Jing'an, , China
Shanxi Bethune Hospital
Taiyuan, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2023313
Identifier Type: -
Identifier Source: org_study_id
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