Effects of Inspiratory and Expiratory Pressure Training Methods in Patients With Chronic Obstructive Pulmonary Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-01-31

Study Completion Date

2016-12-31

Brief Summary

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The study will investigate the effects of different training types ,including combined inspiratory with expiratory pressure threshold training,inspiratory pressure threshold training on patients with chronic obstructive airway disease and investigate whether expiratory pressure threshold training associated with inspiratory pressure threshold training would be better than inspiratory pressure threshold training alone, with regard to exercise capacity, respiratory muscle strength and endurance.

Detailed Description

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We will study 60 patients diagnosed of chronic obstructive pulmonary disease.The monitoring will be done for 8 weeks. Pressure-threshold respiratory trainers were calibrated to provide different loads according to the patients against inspiration (IMST) or expiration (EMST). Those chronic obstructive pulmonary disease clinically stable patients stratified from mild to very severe GOLD stages, were blinded to randomly divided into 3 different groups: a)control group:without any training;b) inspiratory and expiratory pressure threshold training group: trained with the pressure threshold trainer twice time daily with 15minutes' duration;c)inspiratory pressure threshold training group:trained with the pressure threshold trainer twice time daily with 15 minutes' duration,different from the b group,the expiratory pressure threshold is calibrated at 0.

Conditions

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Chronic Obstructive Pulmonary Disease(COPD)

Keywords

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respiratory muscle training respiratory muscle strength respiratory endurance test 6-minute walking test

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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control group

without inspiratory and expiratory pressure threshold training

Group Type NO_INTERVENTION

No interventions assigned to this group

inspiratory pressure training group

The patients will perform daily in 2 sessions of 30 minutes, using a pressure threshold trainer.

Group Type EXPERIMENTAL

inspiratory pressure training group

Intervention Type DEVICE

The respiratory pressure load device can be provided different loads to perform inspiratory and expiratory pressure training.In the study,pressure-threshold respiratory trainers were calibrated to provide different loads against inspiration (IMST) .

mixed training group

The patients will perform daily in 2 sessions of 30 minutes, using a pressure threshold trainer.

Group Type EXPERIMENTAL

mixed training group

Intervention Type DEVICE

The respiratory pressure load device can be provided different loads to perform inspiratory and expiratory pressure training.In the study,pressure-threshold respiratory trainers were calibrated to provide different loads against inspiration (IMST) and expiration(EMST).

Interventions

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inspiratory pressure training group

The respiratory pressure load device can be provided different loads to perform inspiratory and expiratory pressure training.In the study,pressure-threshold respiratory trainers were calibrated to provide different loads against inspiration (IMST) .

Intervention Type DEVICE

mixed training group

The respiratory pressure load device can be provided different loads to perform inspiratory and expiratory pressure training.In the study,pressure-threshold respiratory trainers were calibrated to provide different loads against inspiration (IMST) and expiration(EMST).

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Clinically stable COPD with diagnosis of forced expiratory volume at one second(FEV1)/forced vital capacity(FVC) \< 70%

Exclusion Criteria

Cancer Unstable heart disease Neuromusculoskeletal disorder mental disorder Active smokers

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Xin Chen, Doctor

Role: PRINCIPAL_INVESTIGATOR

Zhujiang Hospital

Locations

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Zhujiang hospital

Guangzhou, Guangdong, China

Site Status

Countries

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China

Central Contacts

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Liqing Wang, Doctor

Role: CONTACT

Phone: +86-02062783391

Email: [email protected]

Facility Contacts

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Liqing Wang

Role: primary

Xin Chen

Role: backup

References

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Xu W, Li R, Guan L, Wang K, Hu Y, Xu L, Zhou L, Chen R, Chen X. Combination of inspiratory and expiratory muscle training in same respiratory cycle versus different cycles in COPD patients: a randomized trial. Respir Res. 2018 Nov 20;19(1):225. doi: 10.1186/s12931-018-0917-6.

Reference Type DERIVED

PMID: 30458805 (View on PubMed)

Other Identifiers

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ZJH21400964

Identifier Type: -

Identifier Source: org_study_id

Effects of Inspiratory and Expiratory Pressure Training Methods in Patients With Chronic Obstructive Pulmonary Disease

Study Results

Basic Information

Brief Summary

Detailed Description

Conditions

Keywords

Study Design

Study Groups

control group

inspiratory pressure training group

inspiratory pressure training group

mixed training group

mixed training group

Interventions

inspiratory pressure training group

mixed training group

Eligibility Criteria

Inclusion Criteria

Exclusion Criteria

Sponsors

Zhujiang Hospital

Responsible Party

Principal Investigators

Xin Chen, Doctor

Locations

Zhujiang hospital

Countries

Central Contacts

Liqing Wang, Doctor

Facility Contacts

Liqing Wang

Xin Chen

References

Xu W, Li R, Guan L, Wang K, Hu Y, Xu L, Zhou L, Chen R, Chen X. Combination of inspiratory and expiratory muscle training in same respiratory cycle versus different cycles in COPD patients: a randomized trial. Respir Res. 2018 Nov 20;19(1):225. doi: 10.1186/s12931-018-0917-6.

Other Identifiers

ZJH21400964