A Multi-Center Study of Rehabilitation to Stable Chronic Obstructive Pulmonary Disease (COPD) Patients
NCT ID: NCT00686660
Last Updated: 2008-06-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
300 participants
INTERVENTIONAL
2007-09-30
2010-09-30
Brief Summary
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* to choose the stable COPD patients in community
* to compare different modes of exercise (cycling and walking)
* to compare the effect of different exercises on the quality of life,exercise endurance,dyspnea and depression
Detailed Description
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1. All patients from four groups will finish baseline investigation and blood sample, including informed consent,questionaires(SGRQ,CRDQ,MRCQ,Depression Scale,etc.),spirometry,6MWT,MIP,MEP,BMI,CRP,TNF,IL-8, etc.Patients in C-WG and C-nonWG will finish cardiopulmonary test.
2. Patients receive 8 weeks training program, includes upper and lower extremities endurance exercises and respiratory muscle endurance exercises. Patients in both CGs cycling at cycle ergometry. Patients in W-WG and W-nonWG walking instead. All patients receive training program twice per year, for two years. Patients were supervised by physicians or nurses at hospital while they are training.
3. In the non-training period, patients in W-WG and C-WG will continue to walk at community, supervised by nurses who call them every month. The other two groups(C-nonWG and W-nonWG) do not receive special requirement on exercise.
4. Telephone call interview will give to patients every month to find whether they have acute exacerbation. Patients are asked to record their activities during daytime in the diary cards.
5. All patients will finish investigation and blood sample after one year and two year,including questionaires,spirometry,6MWT,MIP,MEP,BMI,CRP,TNF,IL-8, etc.Patients in CG will finish cardiopulmonary test.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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1
C-W G: in training period, patients do cycling on cycle ergometry at hospital. in non-training period, patients walk at community.
cycling, walking
In training period, patients do cycling on cycle ergometry. two times per week, 8 weeks per training period, two training period per year, two years.
In non-training period, patients do walking at community. four days per week,18 weeks per non-training period, two non-training period per year, two years.
2
C-nonW G: in training period, patients do cycling at cycle ergometry at hospital, in non-training period, patients don't walk at community.
cycling, non-walking
In training period, patients do cycling. two times a week, 8 weeks per training period, two training period per year, two years.
In non-training period, patients don't receive walk training.
3
W-W G: in training period, patients do walking along 60 meters place at hospital, in non-training period, patients do walking in community
walking, walking
In training period, patients do walking at hospital, two times per week, 8 weeks per training period, two training period per year, two years.
In non-training period, patients do walking at community, four days per week, 18 weeks per non-training period, two non-training period per year, two years.
4
W-nonW G: in training period, patients do walking along 60 meter place, in non-training period,patients don't walk at community.
walking, non-walking
In training period, patients do walking at hospital, two times per week, 8 weeks per training period, two training period per year, two years.
In non-training period, patients don't walking at community.
Interventions
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cycling, walking
In training period, patients do cycling on cycle ergometry. two times per week, 8 weeks per training period, two training period per year, two years.
In non-training period, patients do walking at community. four days per week,18 weeks per non-training period, two non-training period per year, two years.
cycling, non-walking
In training period, patients do cycling. two times a week, 8 weeks per training period, two training period per year, two years.
In non-training period, patients don't receive walk training.
walking, walking
In training period, patients do walking at hospital, two times per week, 8 weeks per training period, two training period per year, two years.
In non-training period, patients do walking at community, four days per week, 18 weeks per non-training period, two non-training period per year, two years.
walking, non-walking
In training period, patients do walking at hospital, two times per week, 8 weeks per training period, two training period per year, two years.
In non-training period, patients don't walking at community.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* 40≤age≤75 years old；
* don't have acute exacerbation in the past one month；
* SpO2 \> 88% at rest；
Exclusion Criteria
* vascular diseases(vasculitis,deep venous thrombosis,varicose veins, etc);
* joint diseases which may affect activities;
* cerebrovascular diseases which may affect activities;
* unstable angina during the past 1 month of acute myocardial infarction in the past 6 months;
* severe arrhythmia;
* cardia insufficiency;
* hypertension which don't control well(systolic pressure\>160mmHg and/or diastolic pressure\> 100mmHg);
* chronic liver or renal insufficiency;
* cognitive handicap.
40 Years
75 Years
ALL
No
Sponsors
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Beijing Tongren Hospital
OTHER
Xuanwu Hospital, Beijing
OTHER
Beijing Fuxing Hospital
UNKNOWN
Peking University First Hospital
OTHER
Beijing Miner General Hospital
UNKNOWN
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
OTHER
Beijing Shuyi Hospital
OTHER
Beijing Daxing Hospital
UNKNOWN
Beijing Huairou Hospital
OTHER
Beijing Chao Yang Hospital
OTHER
Responsible Party
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beijing chaoyang hospital
Principal Investigators
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chen wang, phD
Role: PRINCIPAL_INVESTIGATOR
Beijing Chao Yang Hospital
Locations
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Beijing Chaoyang Hospital
Beijing, Beijing Municipality, China
Countries
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Central Contacts
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Other Identifiers
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COPD rehabilitation CYH 2007
Identifier Type: -
Identifier Source: org_study_id