Prognostic Factors for Surgical Management of Large Hypertensive Basal Ganglionic Haemorrhage

NCT ID: NCT06309940

Last Updated: 2024-03-13

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 25 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-03-31
• Study Completion Date: 2025-04-30

Brief Summary

The aim of this study is to present current and comprehensive recommendations for surgical treatment of this hematoma and to determine the factors that may improve the survival rate

Detailed Description

Spontaneous intracerebral hemorrhage is a common, mostly deadly stroke subtype and accounts for 10% to 15% of all strokes.

It's associated with a higher mortality rate (44% after 30 days) than either ischemic stroke or subarachnoid hemorrhage Up to 75% of the long term survivors are often suffering significant disability and only 12% to 39% of the survivors have favourable neurological functions recovered Rapid diagnosis and attentive management of patients is crucial because early deterioration is common Neurosurgical treatment for ICH has been discussed in recent multicentric studies, but no definitive answer of its utility has emerged.

Improved surgical techniques , neuroimaging, neuroanesthesia and perioperative monitoring and care have all led to improved outcomes from surgery

Conditions

Basal Ganglionic Hemorrhage

Study Design

• Observational Model Type: CASE_CROSSOVER
• Study Time Perspective: CROSS_SECTIONAL

Interventions

Prognostic factors of surgical evacuation of basal ganglionic haemorrhage

Surgical evacuation of basal ganglionic haemorrhage

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• 1) patients aged between 15 and 60 years old ( elderly people>60 years were excluded since their strokes weren't routinely examined by CT scan in the emergency ward, however, in children<15 years old was due mostly to vascular malformations 2) CT scan showed basal ganglionic haemorrhage, with or without intraventricular extension within 24 hr post ictus 3) hematoma volume was 30 ml or above 4) Glasgow Coma Scale scores more than or equal 5 and stable vital signs

Exclusion Criteria

• 1) intracerebral hemorrhage was caused by secondary factors e.g ( vascular malformations or head trauma) 2) GCS less than 5 or multiple intracranial hemorrhage 3) associated visceral disease e.g hepatic or renal or clotting disorder 4) patients with preexisting neurological deficit e.g previous intracerebral hemorrhage or infarction

• Minimum Eligible Age: 15 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Ahmed Sameeh

Resident doctor at neurosurgery Department

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Farrag Mohamed, Doctor

Role: STUDY_CHAIR

Assiut University neurosurgery Department

Central Contacts

Ahmed Sameeh, Master

Role: CONTACT

ahmedsameeh18497@gmail.com

01022690894

Mohamed Abd elbaset, Proffesseur

Role: CONTACT

Khallaf@aun.edu.eg

01006071988

References

McCarron MO, Nicoll JA. Spontaneous intracerebral hemorrhage. N Engl J Med. 2001 Sep 6;345(10):769; author reply 770. doi: 10.1056/NEJM200109063451014. No abstract available.

Reference Type: BACKGROUND

PMID: 11547754 (View on PubMed)

Fernandes HM, Mendelow AD. Spontaneous intracerebral haemorrhage: a surgical dilemma. Br J Neurosurg. 1999 Aug;13(4):389-94. doi: 10.1080/02688699943501.

Reference Type: BACKGROUND

PMID: 10616566 (View on PubMed)

Other Identifiers

Basal ganglionic haemorrhage

Identifier Type: -

Identifier Source: org_study_id