Brain Lesions Following Endovascular and Surgical Treatment of Unruptured Intracranial Aneurysms

NCT ID: NCT01490463

Last Updated: 2013-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Study Classification

OBSERVATIONAL

Study Start Date

2011-08-31

Study Completion Date

2013-01-31

Brief Summary

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The purpose of this study is to determine the incidence and impact of brain lesions in MRI after coiling and clipping of unruptured intracranial aneurysms on clinical and neurological outcome of patients.

Detailed Description

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Silent ischemic lesions after treatment of unruptured intracranial aneurysm (UIA) might alter patients' clinical and neurological outcome. Furthermore silent brain lesions are not well documented after endovascular and surgical treatment of unruptured intracranial aneurysms. Therefore, the investigators investigate the incidence and influence of treatment-related ischemic lesions in magnetic resonance / diffusion-weighted-imaging after endovascular and surgical treatment of UIA.

Conditions

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Unruptured Intracranial Aneurysms

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* diagnosis and treatment of unruptured intracranial aneurysm
* age ≥ 18 yrs
* written informed consent by patients prior to study participation
* willingness to participate in follow-up

Exclusion Criteria

* ruptured intracranial aneurysm
* contraindication for MRI
* Participation in an intervention-/AMG-study
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Department of Neurosurgery, Goethe-University Frankfurt am Main

UNKNOWN

Sponsor Role collaborator

Institute of Neuroradiology, Goethe-University Frankfurt am Main

UNKNOWN

Sponsor Role collaborator

Johann Wolfgang Goethe University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Erdem Güresir

Department of Neurosurgery, Goethe-University Frankfurt am Main

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Neurosurgery, Goethe-University

Frankfurt am Main, Hesse, Germany

Site Status

Countries

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Germany

References

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Platz J, Wagner M, Guresir E, You SJ, Konczalla J, de Rochemont RD, Berkefeld J, Seifert V. Early diffusion-weighted MRI lesions after treatment of unruptured intracranial aneurysms: a prospective study. J Neurosurg. 2017 Apr;126(4):1070-1078. doi: 10.3171/2016.2.JNS152456. Epub 2016 May 20.

Reference Type DERIVED
PMID: 27203140 (View on PubMed)

Other Identifiers

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JohannWGUH_LESUIA

Identifier Type: -

Identifier Source: org_study_id

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