Behavioral and Cognitive Predictors of Persistent Pain and Opioid Misuse in Chronic Pain

NCT ID: NCT06288282

Last Updated: 2025-06-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

130 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-12-20

Study Completion Date

2025-12-31

Brief Summary

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Chronic lower back pain (CLBP) affects approximately 20% of the global population. The study objective is to determine if impulsivity, inhibitory control, drug choice, and/or cognitive distortions predict opioid misuse and disability in patients with chronic pain. This is a prospective consented cross-sectional study characterizing behavioral and cognitive phenotypes using both patient-reported survey measures and cognitive testing. Outcome measures include correlations between impulsivity measures, opioid drug choice responses and cognitive distortion scores, and risk for opioid misuse (Primary outcomes: COMM scores, SOAPPR scores). Secondary outcomes is BPI measurement. A Certificate of Confidentiality will provide additional protections for participants.

Detailed Description

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Conditions

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Chronic Back Pain

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patients with chronic back pain with lumbar, cervical or thoracic spine diagnoses.

No Intervention

Intervention Type OTHER

No intervention will be used.

Interventions

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No Intervention

No intervention will be used.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* With diagnoses related to chronic lower back pain
* Age above 18yrs
* Non pregnant

Exclusion Criteria

* Cancer pain
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Icahn School of Medicine at Mount Sinai

OTHER

Sponsor Role lead

Responsible Party

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Chinwe Nwaneshiudu

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Chinwe Nwaneshiudu

Role: PRINCIPAL_INVESTIGATOR

Icahn School of Medicine at Mount Sinai

Locations

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Mount Sinai Pain management centers

New York, New York, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Chinwe Nwaneshiudu, MD PhD

Role: CONTACT

212 241 4203

Other Identifiers

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STUDY-23-01287

Identifier Type: -

Identifier Source: org_study_id

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