Evaluation of Fluid Responsiveness With Recruitment Maneuver After Sternotomy in Coronary Artery Bypass Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

45 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-01

Study Completion Date

2024-08-20

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Assuming that the basic reliability of dynamic indices will increase with the application of functional hemodynamic tests after sternotomy and protective lung ventilation in patients undergoing elective coronary artery bypass surgery, it is useful to predict fluid responsiveness after sternotomy in coronary artery bypass surgery patients ventilated with 6 ml/kg PBW (ideal body weight). We aimed to reveal the sensitivity and specificity of PPV and SVV changes by applying a lung opening maneuver.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Intraoperative Mechanical Power and Ventilation-Associated Lung Injury: Assessing Complications

NCT06375980

Lung Injury Pulmonary Complication

COMPLETED

Comparison of Airway Management With Bronchial Blocker and Double-Lumen Tube in Single-Lung Ventilation

NCT06299735

Heart Valvular Disease Coronary Arteriosclerosis One-lung Ventilation

RECRUITING NA

Effect of Low-Flow Anesthesia in Single Lung Ventilation on Postoperative Respiratory Complications

NCT06838091

Thoracic Surgery Low-flow Anesthesia

COMPLETED

Anesthesia Management of Coronary Artery Bypass Surgery and Inflammatory Biomarkers

NCT06209437

Coronary Artery Disease Postoperative Complications Anesthesia

COMPLETED

The Effects of Peep and Tidal Volume on Oxidative Stress in Cardiopulmonary Bypass Surgery

NCT03601364

Cardiac Surgery Oxidative Stress

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

In order to evaluate the fluid deficit in patients undergoing coronary artery bypass surgery, researchers will measure stroke volume index, cardiac index and mean arterial pressure while the patients are in the lima position.

Then researchers will perform a lung opening maneuver (30mmHg for 30 seconds) and measure again.

researchers will measure again after the values return to normal. researchers will give patients balanced fluid at 3ml/kg and record their values.

Can researchers predict fluid response with lung opening maneuver?

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Fluid Therapy Coronary Artery Bypass Surgery Patients Lung Recruitment Maneuver

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

patients who will have coroner arter bypass surgeon

Patients undergoing coronary artery bypass surgery will be eliminated if there are exclusion criteria. Patients who do not have exclusion criteria will be included in the study if they agree to volunteer.

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 1-ASA2-3 patients between the ages of 18-80 who will undergo elective coronary bypass surgery under general anesthesia

Exclusion Criteria

* 1\. Be younger than 18 years old, be over 80 years old
* 2\. Patients with an ASA score greater than 3
* 3\. EF\<40%
* 4\. Those with contraindications to anesthetic drugs
* 5\. Patients with BMI\>30
* 6\. Patients who did not want to participate in the study
* 7\. Right ventricular dysfunction
* 8\. COPD(Chronic obstructive pulmonary disease)
* 9\. Bullous lung disease
* 10\. Moderate to severe PHT
* 11\. Severe kidney or liver disease
* 12\. Patients with hemodynamic instability in the perioperative period
* 13\. Pregnancy

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No