Primary Subtalar Arthrodesis for Calcaneal Fractures

NCT ID: NCT06249126

Last Updated: 2025-12-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

218 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-09-02

Study Completion Date

2026-12-31

Brief Summary

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Management of severe injuries to the heel (displaced intra-articular calcaneus fractures) continues to be a major challenge for orthopedic surgeons. Previous studies have demonstrated poor outcomes, and results show that patients experience long-term pain and decreased quality of life postoperatively. Poor outcomes are driven by pain, in particular, which is linked to post-traumatic subtalar arthritis.

Detailed Description

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The goal of this clinical trial is to compare two surgical options for calcaneus fractures to determine best treatment for returning to work sooner in adults.

Participants will be randomized to one of two treatment options and will be asked to complete patient reported outcome measure surveys.

Researchers will compare Open Reduction and Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA) to ORIF alone to see which group returns to work at an earlier timepoint.

Conditions

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Calcaneus Fracture

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA)

Surgical fixation by joint fusion + Surgical fixation with plates and screws, plates, sutures, or rods are used to hold the broken bone together

Group Type OTHER

Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA)

Intervention Type PROCEDURE

Definitive fixation by joint fusion

Open Reduction Internal Fixation (ORIF) only

Surgical fixation with plates and screws, plates, sutures, or rods are used to hold the broken bone together

Group Type OTHER

Open Reduction Internal Fixation (ORIF) only

Intervention Type PROCEDURE

Definitive fixation with plates and screws

Interventions

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Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA)

Definitive fixation by joint fusion

Intervention Type PROCEDURE

Open Reduction Internal Fixation (ORIF) only

Definitive fixation with plates and screws

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Undergoing operative treatment for displaced intra-articular calcaneus fracture
* Sanders III and IV displaced intra-articular calcaneus fracture OR Sanders II with any of the following criteria: Bohler angle \< 0 degrees, open fracture, pain syndrome, substance use disorder
* Age 18 or older
* Able to follow up at site for 1 year

Exclusion Criteria

* Planned surgery using extensile lateral approach
* Sanders II displaced intra-articular calcaneus fracture without: Bohler angle \< 0 degrees, open fracture, pain syndrome, or substance
* \<18 years of age
* Body Mass Index (BMI) \>40
* Unable to follow up at site for 1 year
* Patients that speak neither English or Spanish
* Prisoner
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wake Forest University Health Sciences

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joseph R Hsu, MD

Role: PRINCIPAL_INVESTIGATOR

Wake Forest University Health Sciences

Locations

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Emory University, Grady Memorial Research Hospital

Atlanta, Georgia, United States

Site Status NOT_YET_RECRUITING

Atrium Health Navicent

Macon, Georgia, United States

Site Status RECRUITING

University of Kentucky

Lexington, Kentucky, United States

Site Status NOT_YET_RECRUITING

Louisiana State University - University Medical Center New Orleans

New Orleans, Louisiana, United States

Site Status NOT_YET_RECRUITING

University of Maryland Medical Center

Baltimore, Maryland, United States

Site Status RECRUITING

NYC Health and Hospital/Bellevue

New York, New York, United States

Site Status NOT_YET_RECRUITING

University of North Carolina Chapel Hill

Chapel Hill, North Carolina, United States

Site Status NOT_YET_RECRUITING

Atrium Health Carolinas Medical Center

Charlotte, North Carolina, United States

Site Status RECRUITING

OrthoCarolina Foot and Ankle Institute

Charlotte, North Carolina, United States

Site Status RECRUITING

Atrium Health Cabarrus

Concord, North Carolina, United States

Site Status RECRUITING

Atrium Health Wake Forest Baptist

Winston-Salem, North Carolina, United States

Site Status NOT_YET_RECRUITING

Prisma Health

Greenville, South Carolina, United States

Site Status NOT_YET_RECRUITING

Vanderbilt University Medical Center

Nashville, Tennessee, United States

Site Status NOT_YET_RECRUITING

The University of Texas Medical Branch

Galveston, Texas, United States

Site Status NOT_YET_RECRUITING

Countries

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United States

Central Contacts

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Christine Churchill

Role: CONTACT

704-355-6947

Facility Contacts

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Morgan Fuller

Role: primary

404-251-8953

Jason Barron

Role: backup

Jarrod Dumpe, MD

Role: primary

Adithi Shyam

Role: backup

Paul Matuszewski, MD

Role: primary

859-323-5533

Matthew Eubank

Role: backup

Carolyn Bridgman

Role: primary

Mark Gage, MD

Role: primary

Andrea Howe

Role: backup

Nina Fisher, MD

Role: primary

Ivanka Bhambhani

Role: backup

Andrew Chen, MD

Role: primary

Rachel B Seymour, PhD

Role: primary

Christine Churchill, MA

Role: backup

Samuel E Ford, MD

Role: primary

Zach Hutchko

Role: backup

Luke Harmer, MD

Role: primary

Erica Grochowski, MPH

Role: backup

Martha Holden

Role: primary

Kyle Jeray, MD

Role: primary

Emily Williams

Role: backup

Bethany Gallagher, MD

Role: primary

Karen Trochez

Role: backup

Joseph Wenke, MD

Role: primary

Other Identifiers

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HT94252310505

Identifier Type: OTHER

Identifier Source: secondary_id

IRB00107954

Identifier Type: -

Identifier Source: org_study_id

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