Impact of Modified Feeding Protocol on Neonatal Outcomes

NCT ID: NCT06246032

Last Updated: 2024-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-01

Study Completion Date

2024-06-30

Brief Summary

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The goal of this clinical trial is to compare modified feeding protocol and current feeding protocol on neonatal outcomes in preterm infants who born with weight less than 2kg.

The main questions it aims to answer are:

* Is Modified feeding protocol will decrease the duration of parenteral nutrition and length of hospital stay?
* Is Modified feeding protocol feasible, efficient, and safe in preterm infants?

Participants will undergo the modified feeding protocol since birth until discharge.

Detailed Description

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two group in this study Prospective group: intervention group will undergo the modified feeding protocol Retrospective group: intervention group will undergo the current feeding protocol

Both group will have care as routine care to this kind of patients But the differ will be in feeding protocol as initiation rate, advancement rate, human milk fortification rate

The outcomes of both group will be compeered to meet the study objectives

Conditions

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Preterm Birth Weight Feeding Disorder Neonatal

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Caregivers

Study Groups

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Modified feeding Protocol

Prospective

Group Type EXPERIMENTAL

Modified feeding Protocol

Intervention Type OTHER

Initiation of feeding (fixed): 10cc/kg

Advancement based on birthweight (fixed):

\<750g: 15cc/kg/d 750-999g: 20cc/kg/d 1000-1249g: 25cc/kg/d 1250-1499g: 25cc/kg/d 1500-1749g: 35cc/kg/d 1750-2000g: 35cc/kg/d

Starting Human milk fortification when feed reach at 70cc/kg/d

Current feeding Protocol

Retrospective data will be collected from medical record of patients undergo the current feeding protocol as follow

Initiation of feeding (average):

8.7cc/kg (6-12cc/kg)

Advancement based on birthweight (average):

\<750g: 20cc/kg/d (17-24cc/kg/d) 750-999g: 29cc/kg/d (25-34cc/kg/d) 1000-1249g: 22cc/kg/d (20-24cc/kg/d) 1250-1499g: 24cc/kg/d (21-25cc/kg/d) 1500-1749g: 20cc/kg/d (18-21cc/kg/d) 1750-2000g: 34cc/kg/d (32-36cc/kg/d)

Starting Human milk fortification when feed reach at 120cc/kg/d

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Modified feeding Protocol

Initiation of feeding (fixed): 10cc/kg

Advancement based on birthweight (fixed):

\<750g: 15cc/kg/d 750-999g: 20cc/kg/d 1000-1249g: 25cc/kg/d 1250-1499g: 25cc/kg/d 1500-1749g: 35cc/kg/d 1750-2000g: 35cc/kg/d

Starting Human milk fortification when feed reach at 70cc/kg/d

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Birth weight (\<2000g)
* Gestational Age (\<37 week)

Exclusion Criteria

* Metabolic Disorders
* Congenital Heart Diseases
* Chronic Lung Disease
* Congenital Anomalies (can related to feeding)
* Moderate to severe GERD
* Necrotizing enterocolitis stage 3 (surgical)
* Gastrointestinal surgery
Maximum Eligible Age

2 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Imam Abdulrahman Bin Faisal University

OTHER

Sponsor Role lead

Responsible Party

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Hanan AlQahtani

Clinical Dietitian

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hanan AlQahtani, Master

Role: PRINCIPAL_INVESTIGATOR

Imam Abdulrahman Bin Faisal University

Locations

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Maternity and Children Hospital

Dammam, Eastern Province, Saudi Arabia

Site Status

Countries

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Saudi Arabia

Other Identifiers

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IRB-PGS-2023-03-443

Identifier Type: -

Identifier Source: org_study_id

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