CARegiver BURden, Effectiveness and Other Health Care Measures on Functional Disability, in Patients Treated With Abobotulinumtoxin A for Upper Limb Spasticity

NCT ID: NCT06245772

Last Updated: 2026-01-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

113 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-16

Study Completion Date

2027-02-28

Brief Summary

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The aim of this study is to perform, in real world clinical practice, a three-dimensional assessment from patient's, caregiver's and physician's perspectives, of the impact of AboBoNT-A on caregiver burden, functional disability and other health care measures in patients affected with ULS due to acquired brain injuries.

Detailed Description

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Conditions

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Upper Limb Injury

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. The patient is able to comply with the protocol;
2. Male and female patients who are at least 18 years old;
3. The patient is supported by an identified caregiver (family member or other nonpaid adult

\- if the patient has more than one caregiver, the main caregiver will be selected) who provides daily supervision or direct assistance to the care recipient;
4. The patient has been diagnosed with ULS due to non-progressive acquired brain injuries (stroke, traumatic brain injury, surgical resection of non-progressive tumours, other) or due to non-progressive spinal cord injury with stability of spasticity of the upper limbs;
5. The decision to treat the patient with AboBoNT-A by the care provider will be made prior to, and independently from the decision to enrol the patient in the observational study;
6. The patient is covered by a healthcare insurance;
7. The cognitive and health status of the patient is compatible with the participation to the study.

For Caregivers :

(8) The caregiver is able to comply with the protocol; (9) Male and female caregivers who are at least 18 years old; (10) The cognitive and health status of the caregiver is compatible with the participation to the study.

Exclusion Criteria

1. Contraindication to BoNT-A treatment;
2. Previously treated with BoNT-A in upper limbs within the last 12 months;
3. Patients and if applicable Legally Authorized Representative (LAR) of patient under curatorship or deprived of liberty who are opposed to their data collection
4. Caregivers who are opposed to their data collection;
5. Caregivers already included for another patient;
6. Current participation in any other interventional clinical study or have participated within the 12 weeks prior to the inclusion visit;
7. Non-ambulatory patients except for those who have been hospitalized for the purpose of their BoNT-A injection (maximum length of stay as per clinical judgment of the investigator);
8. Vulnerable patients (i.e. pregnant and/or lactating women, children, patient under curatorship or deprived of liberty).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ipsen

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ipsen Medical Director

Role: STUDY_DIRECTOR

Ipsen

Locations

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CH Bagnères

Bagnères-de-Bigorre, , France

Site Status RECRUITING

CH Bar le Duc

Bar-le-Duc, , France

Site Status RECRUITING

Besançon - CHU/CRRF de Bréguille/Salin les bains

Besançon, , France

Site Status RECRUITING

CHU Bordeaux - Hopital Tastet-Girard

Bordeaux, , France

Site Status RECRUITING

CH Bourg en Bresse

Bourg-en-Bresse, , France

Site Status RECRUITING

CHU Brest

Brest, , France

Site Status RECRUITING

SSR Tour de Gassies

Bruges, , France

Site Status WITHDRAWN

CH Colmar

Colmar, , France

Site Status WITHDRAWN

Centre de rééducation des 3 vallées

Corbie, , France

Site Status NOT_YET_RECRUITING

CH Dax

Dax, , France

Site Status RECRUITING

CRF DIivio Dijon

Dijon, , France

Site Status WITHDRAWN

Fondation hopale - Fouqière-lez-Lens

Fouquières-lès-Lens, , France

Site Status RECRUITING

Clinique de Verdaich

Gaillac-Toulza, , France

Site Status RECRUITING

Garches

Garche, , France

Site Status WITHDRAWN

Groupe Hospitalier De Gonesse

Gonesse, , France

Site Status WITHDRAWN

HCL - Renée Sabran

Hyères, , France

Site Status RECRUITING

Crf Bel Air

La Membrolle-sur-Choisille, , France

Site Status RECRUITING

CHU Lille

Lille, , France

Site Status RECRUITING

Clinique Saint Martin Sud

Marseille, , France

Site Status WITHDRAWN

CHU Montpellier

Montpellier, , France

Site Status WITHDRAWN

CHU Nice

Nice, , France

Site Status RECRUITING

CHU Nîmes

Nîmes, , France

Site Status ACTIVE_NOT_RECRUITING

Hôpital Rothschild

Paris, , France

Site Status RECRUITING

Ste Anne

Paris, , France

Site Status RECRUITING

Hôpital Fondation Adolphe de Rothschild

Paris, , France

Site Status ACTIVE_NOT_RECRUITING

CHU Reims

Reims, , France

Site Status RECRUITING

CHU Rennes

Rennes, , France

Site Status RECRUITING

Pole St Hélier

Rennes, , France

Site Status RECRUITING

Fondation Ildys - Roscoff

Roscoff, , France

Site Status RECRUITING

CH Saint Denis

Saint-Denis, , France

Site Status WITHDRAWN

SSR Val Rosay UGECAM

Saint-Didier-au-Mont-d'Or, , France

Site Status RECRUITING

CH Ariège Couserans Site de Rozès

Saint-Girons, , France

Site Status RECRUITING

CH Saint Jean de Luz

Saint-Jean-de-Luz, , France

Site Status RECRUITING

Le Centre Médical Germaine Revel

Saint-Maurice-sur-Dargoire, , France

Site Status WITHDRAWN

CHU Amiens

Salouël, , France

Site Status WITHDRAWN

CHU Toulouse

Toulouse, , France

Site Status RECRUITING

CH Troyes

Troyes, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Ipsen Clinical Study Enquiries

Role: CONTACT

See e mail

Other Identifiers

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CLIN-52120-459

Identifier Type: -

Identifier Source: org_study_id

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