The Prognostic Value of Tertiary Lymphatic Structure in Esophageal Squamous Cell Carcinoma

NCT ID: NCT06241066

Last Updated: 2024-02-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

359 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-01

Study Completion Date

2023-10-31

Brief Summary

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Retrospective analysis of the presence and maturity of tertiary lymphoid structures in pathological sections of patients with esophageal squamous cell carcinoma after surgical treatment. Pay attention to the overall survival and disease free survival of these esophageal squamous cell carcinoma patients.

Detailed Description

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Conditions

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Esophageal Squamous Cell Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Surgery alone group

Patients who were diagnosed with esophageal squamous cell carcinoma and underwent esophageal squamous cell carcinoma resection without any prior treatment are included in this group. These patients had not been diagnosed with any other cancer. Finally, 96 patients were included.

no-Intervention

Intervention Type OTHER

no-Intervention

Neoadjuvant chemotherapy group

Patients who were diagnosed with esophageal squamous cell carcinoma and underwent esophageal squamous cell carcinoma resection, and underwent routine chemotherapy before surgery were included in this group. These patients were not diagnosed with any other cancers Finally, 89 patients were included.

no-Intervention

Intervention Type OTHER

no-Intervention

Neoadjuvant chemotherapy combined with immunotherapy group

Patients who were diagnosed with esophageal squamous cell carcinoma and underwent esophageal squamous cell carcinoma resection, and underwent routine chemotherapy combined with immunotherapy before surgery were included in this group. These patients were not diagnosed with any other cancers Finally, 81 patients were included.

no-Intervention

Intervention Type OTHER

no-Intervention

Neoadjuvant chemotherapy combined with radiotherapy group

Patients who were diagnosed with esophageal squamous cell carcinoma and underwent esophageal squamous cell carcinoma resection, and underwent routine chemotherapy combined with radiotherapy before surgery were included in this group. These patients were not diagnosed with any other cancers Finally, 93 patients were included.

no-Intervention

Intervention Type OTHER

no-Intervention

Interventions

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no-Intervention

no-Intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 1\. Pathologically diagnosed as esophageal squamous cell carcinoma; 2. Surgery for esophageal cancer; 3. Complete medical records;

Exclusion Criteria

* Patients with a previous history of malignant tumor
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tianjin Medical University Cancer Institute and Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Wencheng Zhang, M.D.

Role: PRINCIPAL_INVESTIGATOR

Tianjin Medical University Cancer Institute and Hospital

Locations

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Tianjin Cancer Hospital

Tianjin, Tianjin Municipality, China

Site Status

Countries

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China

Other Identifiers

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bc2023192

Identifier Type: -

Identifier Source: org_study_id

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