Multi-institutional Analysis of Survival and Recurrence Patterns of Different Pathological Regression Types After Neoadjuvant Chemoradiotherapy or Radiotherapy for Esophageal Squamous Cell Carcinoma

NCT ID: NCT06241079

Last Updated: 2024-02-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

582 participants

Study Classification

OBSERVATIONAL

Study Start Date

2003-03-31

Study Completion Date

2023-02-01

Brief Summary

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The goal of this multicenter retrospective cohort study is to evaluate the impact of different pathological regression types on survival and recurrence patterns, with a particular focus on ypT0N+ patients in patients with esophageal squamous cell carcinoma. The main questions it aims to answer are the survival and recurrence patterns among the different pathological regression types in patients with esophageal squamous cell carcinoma after neoadjuvant chemoradiotherapy.

Detailed Description

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Conditions

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Esophageal Squamous Cell Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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ypT0N0

non-intervention

Intervention Type OTHER

non-intervention

ypT0N+

non-intervention

Intervention Type OTHER

non-intervention

ypT+N0

non-intervention

Intervention Type OTHER

non-intervention

ypT+N+

non-intervention

Intervention Type OTHER

non-intervention

Interventions

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non-intervention

non-intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* histologically confirmed potentially resectable ESCC, clinical stage T1-4N0-1M0 (stage I-III) according to the American Joint Committee on Cancer 6th edition staging criteria.

Exclusion Criteria

* incomplete surgical resection, two-dimensional radiotherapy, and incomplete clinical data.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chinese Academy of Medical Sciences

OTHER

Sponsor Role collaborator

Sichuan Cancer Hospital and Research Institute

OTHER

Sponsor Role collaborator

Tianjin Medical University Cancer Institute and Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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bc2023183

Identifier Type: -

Identifier Source: org_study_id

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