The Stockholm CREAtinine Measurements Project

NCT ID: NCT06239129

Last Updated: 2024-02-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

3200000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-01-01

Study Completion Date

2022-12-31

Brief Summary

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The Stockholm CREAtinine Measurements (SCREAM) project is a healthcare utilization cohort including, at present, all adult residents in Stockholm between 2006 and 2021. The region of Stockholm had a population of 2.3 million citizens in 2021and provides universal healthcare with a single unified health-system. Administrative databases with complete information on socidemographic data, healthcare use, diagnoses and therapeutic/surgical procedures, and vital status were enriched with performed laboratory tests, dispensed prescriptions at Swedish pharmacies and validated kidney replacement therapy endpoints. Registries were linked and de-identified by the Swedish National Board of Welfare and are considered to have no or minimal loss to follow-up. Because the study utilized de-identified data, it was deemed not to require informed consent and was approved by the regional ethical review boards and the Swedish National Board of Welfare.

For detailed description of available data and linked registers please consult:

https://pubmed.ncbi.nlm.nih.gov/35028991/

Detailed Description

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Please consult cohort description in:

https://pubmed.ncbi.nlm.nih.gov/35028991/ https://pubmed.ncbi.nlm.nih.gov/26798472/

Conditions

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Chronic Kidney Diseases Acute Kidney Injury Diabetes Mellitus Cardiovascular Diseases Hypertension

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Initiation of specific medications

multiple therapies studied within this database

Intervention Type DRUG

Undertaking of specific procedures

multiple procedures/surgeries studied within this database

Intervention Type PROCEDURE

Abnormalities in specific laboratory tests

multiple abnormalities in laboratory values (i.e. CRP, cholesterol, eGFR, potassium) studied within this database

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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multiple therapies studied within this database

Eligibility Criteria

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Inclusion Criteria

For both cohorts:

Be a resident of Stockholm during 2006-2021, of all ages

For the primary cohort:

To have undertaken at least one test of serum creatinine or albuminuria during 2006-2021. If this condition is met, we will then extract a broad range of laboratory tests

For the secondary cohort:

Anyone not undertaking a test of serum creatinine or albuminuria will conform the secondary cohort. In this cohort we will not extract any other laboratory test, but will obtain the rest of healthcare information

Exclusion Criteria

None
Minimum Eligible Age

0 Years

Maximum Eligible Age

110 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Region Stockholm

OTHER_GOV

Sponsor Role collaborator

Karolinska Institutet

OTHER

Sponsor Role lead

Responsible Party

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Juan Jesus Carrero

Professor of Cardiorenal Epidemiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Juan J Carrero, Prof

Role: PRINCIPAL_INVESTIGATOR

Karolinska Institutet

References

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Russel WA, Fu EL, Bosi A, Caldinelli A, Inker LA, Chang AR, Levey AS, Carrero JJ. Obesity, Underweight, and Accuracy of eGFR Using Cystatin C and Creatinine in a Northern European Population. J Am Soc Nephrol. 2025 Jun 13. doi: 10.1681/ASN.0000000760. Online ahead of print. No abstract available.

Reference Type DERIVED
PMID: 40512561 (View on PubMed)

Other Identifiers

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000001

Identifier Type: -

Identifier Source: org_study_id

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