Screening for Chronic Kidney Disease (CKD) Among Older People Across Europe (SCOPE)

NCT ID: NCT02691546

Last Updated: 2020-06-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2434 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-08-08

Study Completion Date

2020-03-10

Brief Summary

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The SCOPE study is an observational, multicenter, prospective cohort study aimed at evaluating a 2-year screening programme for CKD in a population of older patients, aged 75 years or more, in seven European Countries, in an attempt to investigate whether and to which extent currently available screening methods may identify older people at risk of worsening kidney function.

Detailed Description

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Conditions

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Chronic Kidney Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Subjects aged 75 years or older

blood sample collection

Intervention Type OTHER

Interventions

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blood sample collection

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age≥75 years
* subjects attending the outpatient services at participating institutions

Exclusion Criteria

* ESRD or dialysis
* history of solid organ or bone marrow transplantation
* active malignancy within 24 months prior to screening or metastatic cancer
* life expectancy less than 6 months
* severe cognitive impairment (MMSE\<10),
* any medical or other reason that the subject is unsuitable for the study
* subjects unwilling to provide consent
Minimum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ben-Gurion University of the Negev

OTHER

Sponsor Role collaborator

Erasmus Medical Center

OTHER

Sponsor Role collaborator

Medical University of Graz

OTHER

Sponsor Role collaborator

Servicio Madrileño de Salud, Madrid, Spain

OTHER

Sponsor Role collaborator

Institut Catala de Salut

OTHER_GOV

Sponsor Role collaborator

UNIVERSYTET MEDYCZNY W LODZI

UNKNOWN

Sponsor Role collaborator

Friedrich-Alexander-Universität Erlangen-Nürnberg

OTHER

Sponsor Role collaborator

Uppsala University

OTHER

Sponsor Role collaborator

Istituto Nazionale di Ricovero e Cura per Anziani

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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MEDIZINISCHE UNIVERSITAT- Internal Medicine/Nephrology/Geriatric Department

Graz, , Austria

Site Status

FRIEDRICH-ALEXANDER-UNIVERSITAT-Institute for Biomedicine of Aging

Erlangen, , Germany

Site Status

BEN-GURION UNIVERSITY-Geriatrics Department

Beersheba, , Israel

Site Status

INRCA Research Hospital

Ancona, , Italy

Site Status

INRCA Research Hospital

Cosenza, , Italy

Site Status

ERASMUS UNIVERSITAIR MEDISCH CENTRUM-Department of Internal Medicine

Rotterdam, , Netherlands

Site Status

UNIVERSYTET MEDYCZNY-Department of Geriatrics

Lodz, , Poland

Site Status

INSTITUT CATALA DE LA SALUT-Internal Medicine Deparment

Barcelona, , Spain

Site Status

SERVICIO MADRILENO DE SALUD-Geriatric Department

Madrid, , Spain

Site Status

Countries

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Austria Germany Israel Italy Netherlands Poland Spain

References

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Freiberger E, Fabbietti P, Corsonello A, Lattanzio F, Sieber C, Tap L, Mattace-Raso F, Arnlov J, Carlsson AC, Roller-Wirnsberger R, Wirnsberger G, Moreno-Gonzalez R, Formiga F, Martinez SL, Gil P, Kostka T, Guligowska A, Yehoshua I, Melzer I, Kob R; SCOPE investigators. Short physical performance battery is not associated with falls and injurious falls in older persons: longitudinal data of the SCOPE project. Eur Geriatr Med. 2024 Jun;15(3):831-842. doi: 10.1007/s41999-024-00941-y. Epub 2024 Feb 28.

Reference Type DERIVED
PMID: 38416398 (View on PubMed)

Freiberger E, Fabbietti P, Corsonello A, Lattanzio F, Artzi-Medvedik R, Kob R, Melzer I; SCOPE consortium; Britting S. Transient versus stable nature of fear of falling over 24 months in community-older persons with falls- data of the EU SCOPE project on Kidney function. BMC Geriatr. 2022 Aug 23;22(1):698. doi: 10.1186/s12877-022-03357-0.

Reference Type DERIVED
PMID: 35999522 (View on PubMed)

Tap L, Corsonello A, Formiga F, Moreno-Gonzalez R, Arnlov J, Carlsson AC, Roller-Wirnsberger R, Wirnsberger G, Ziere G, Freiberger E, Sieber C, Kostka T, Guligowska A, Gil P, Martinez SL, Artzi-Medvedik R, Yehoshua I, Fabbietti P, Lattanzio F, Mattace-Raso F; SCOPE investigators. Is kidney function associated with cognition and mood in late life? : The Screening for CKD among Older People across Europe (SCOPE) study. BMC Geriatr. 2020 Oct 2;20(Suppl 1):297. doi: 10.1186/s12877-020-01707-4.

Reference Type DERIVED
PMID: 33008359 (View on PubMed)

Britting S, Artzi-Medvedik R, Fabbietti P, Tap L, Mattace-Raso F, Corsonello A, Lattanzio F, Arnlov J, Carlsson AC, Roller-Wirnsberger R, Wirnsberger G, Kostka T, Guligowska A, Formiga F, Moreno-Gonzalez R, Gil P, Martinez SL, Kob R, Melzer I, Freiberger E; SCOPE investigators. Kidney function and other factors and their association with falls : The screening for CKD among older people across Europe (SCOPE) study. BMC Geriatr. 2020 Oct 2;20(Suppl 1):320. doi: 10.1186/s12877-020-01698-2.

Reference Type DERIVED
PMID: 33008307 (View on PubMed)

Corsonello A, Fabbietti P, Formiga F, Moreno-Gonzalez R, Tap L, Mattace-Raso F, Roller-Wirnsberger R, Wirnsberger G, Arnlov J, Carlsson AC, Weingart C, Freiberger E, Kostka T, Guligowska A, Gil P, Martinez SL, Melzer I, Yehoshua I, Lattanzio F; SCOPE investigators. Chronic kidney disease in the context of multimorbidity patterns: the role of physical performance : The screening for CKD among older people across Europe (SCOPE) study. BMC Geriatr. 2020 Oct 2;20(Suppl 1):350. doi: 10.1186/s12877-020-01696-4.

Reference Type DERIVED
PMID: 33008303 (View on PubMed)

Corsonello A, Tap L, Roller-Wirnsberger R, Wirnsberger G, Zoccali C, Kostka T, Guligowska A, Mattace-Raso F, Gil P, Fuentes LG, Meltzer I, Yehoshua I, Formiga-Perez F, Moreno-Gonzalez R, Weingart C, Freiberger E, Arnlov J, Carlsson AC, Bustacchini S, Lattanzio F; SCOPE investigators. Design and methodology of the screening for CKD among older patients across Europe (SCOPE) study: a multicenter cohort observational study. BMC Nephrol. 2018 Oct 11;19(1):260. doi: 10.1186/s12882-018-1030-2.

Reference Type DERIVED
PMID: 30309342 (View on PubMed)

Other Identifiers

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Grant Agreement n. 634869

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

INRCA_01_2016

Identifier Type: -

Identifier Source: org_study_id

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