Effect of PVE on Surgical Outcomes and Long-term Survival in Perihilar Cholangiocarcinoma

NCT ID: NCT06222619

Last Updated: 2024-01-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

136 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-30

Study Completion Date

2023-08-30

Brief Summary

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Portal vein embolization is often recommended to reduce the risk of postoperative liver failure and mortality. In this retrospective cohort study, researchers investigated the effect of portal vein embolization in patients with resectable perihilar cholangiocarcinoma bismuth type III and IV.

Detailed Description

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Conditions

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Biliary Tract Cancer Portal Vein Embolization

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Resection without PVE

Resection of bile duct and associated hemi-liver without portal vein embilzation

No interventions assigned to this group

Resection after PVE

Resection of bile duct and associated hemi-liver after portal vein embilzation

Potal vein embilization

Intervention Type PROCEDURE

Portal vein of involved bile duct is embolized to increase the volume of remnant liver.

No resection after PVE

No resection of bile duct and associated hemi-liver after portal vein embilzation

Potal vein embilization

Intervention Type PROCEDURE

Portal vein of involved bile duct is embolized to increase the volume of remnant liver.

Interventions

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Potal vein embilization

Portal vein of involved bile duct is embolized to increase the volume of remnant liver.

Intervention Type PROCEDURE

Other Intervention Names

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Surgical resection

Eligibility Criteria

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Inclusion Criteria

1. patients with Bismuth type III or IV stricture on radiological examination, including computed tomography (CT) or magnetic resonance cholangiography
2. patients with perihilar cholangiocarcinoma histologically confirmed by surgical resection or forceps biopsy/brush cytology under endoscopic retrograde cholangiopancreatography or through the percutaneous transhepatic biliary drainage tract.

Exclusion Criteria

1. patients with unresectable perihilar cholangiocarcinoma
2. patients who refused treatment
3. patients with other concomitant malignancies.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Sang Hyub Lee

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Seoul National University Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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H-2001-092-1095

Identifier Type: -

Identifier Source: org_study_id

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