The Addition of Hydromorphone to Local Anesthetics for the Repair of Inguinal Hernias in Elderly Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

63 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-11-01

Study Completion Date

2023-12-25

Brief Summary

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To compare the clinical and postoperative analgesic effects of hydromorphone combined with ropivacaine and ropivacaine alone in quadrangular muscle block for open inguinal hernia in elderly patients.

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Detailed Description

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Elderly patients selected for Lichtenstein hernia repair in our hospital who met the inclusion and exclusion criteria and obtained informed consent were included in this trial, and were randomly divided into experimental group by random number table method: 0.375% ropivacaine combined with hydromorphone block group, and control group: 0.375% ropivacaine block group alone.

Conditions

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Inguinal Hernia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Hydromorphone combined with ropivacaine

The posterior quadrat block was performed by adding 1mg hydromorphone to 0.375% ropivacaine in a total of 30ml.

Group Type EXPERIMENTAL

Hydromorphone combined with ropivacaine

Intervention Type DRUG

1mg hydromorphone was added to 0.375% ropivacaine for a total of 30ml to perform quadrat block

ropivacaine

A mixture of 0.375% ropivacaine for a total of 30ml was performed for posterior quadrate block.

Group Type ACTIVE_COMPARATOR

Ropivacaine

Intervention Type DRUG

A mixture of 0.375% ropivacaine for a total of 30ml was used for quadrate block

Interventions

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Hydromorphone combined with ropivacaine

1mg hydromorphone was added to 0.375% ropivacaine for a total of 30ml to perform quadrat block

Intervention Type DRUG

Ropivacaine

A mixture of 0.375% ropivacaine for a total of 30ml was used for quadrate block

Intervention Type DRUG

Other Intervention Names

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Quadratus lumbois block Quadratus lumbois block

Eligibility Criteria

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Inclusion Criteria

* Age 60 and above.
* Admission to hospital for open inguinal hernia surgery is consistent with the -indications of this surgical modality, ASA grades 1 to 3.
* No recent use of sedatives, opioids, or other analgesics.
* Good compliance, signed informed consent.
* Complete clinical data.

Exclusion Criteria

* There are serious cardiovascular and cerebrovascular diseases.
* Abdominal infection.
* Coagulation dysfunction or receiving anticoagulation therapy.
* Local anesthesia drug allergy.
* Can not cooperate with the corresponding operation, suffering from mental illness.
* Previous surgical history of the corresponding position in the abdomen that may interfere with the surgical process of this study.

Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No