Effects of Crossover Point Exercise on Vascular Function of Women in Different Menopausal Years

NCT ID: NCT06201312

Last Updated: 2024-01-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-11

Study Completion Date

2024-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Recruit postmenopausal women and randomly assign them to one of four groups: Early Postmenopausal Exercise Group (EE), Late Postmenopausal Exercise Group (LE), Early Postmenopausal Control Group (EC), and Late Postmenopausal Control Group (LC).

All participates will undergo a graded exercise test to determine their maximum oxygen uptake, and vascular function response will be measured immediately after the exercise test. The COP exercise intensity for postmenopausal women will be obtained through the exercise test, and subjects in the EE and LE groups will undergo exercise training at this intensity for a period of three months. Tests and analyses of relevant indicators will be conducted on subjects in all four groups before and after the intervention. The exercise load experiments will be performed on a cycle ergometer.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Vascular Health

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Early Postmenopausal Exercise Group (EE)

Group Type EXPERIMENTAL

COP exercise

Intervention Type OTHER

crossover point intensity exercise

Late Postmenopausal Exercise Group (LE)

Group Type EXPERIMENTAL

COP exercise

Intervention Type OTHER

crossover point intensity exercise

Early Postmenopausal Control Group (EC)

Group Type NO_INTERVENTION

No interventions assigned to this group

Late Postmenopausal Control Group (LC)

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

COP exercise

crossover point intensity exercise

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Postmenopausal women without cardiovascular disease

Exclusion Criteria

* Women with undetermined menopause
* BMI \<18.5 kg/m2 or BMI \>28 kg/m2
* fasting plasma triglyceride levels ≥500 mgdl
* diabetes mellitus or fasting glucose \>140 mgd
* blood creatinine \>2.0 mgdl
* uncontrolled hypertension (systolic blood pressure \>160 mmHg and/or diastolic blood pressure \>110 mmHg)
* untreated thyroid disease
* life-threatening illness with a prognosis of \<5 years;
* history of deep vein thrombosis,
* pulmonary embolism, or breast cancer;
* currently receiving estrogen therapy.
Minimum Eligible Age

45 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Beijing Sport University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

School of Sports Medicine and Rehabilitation, Beijing Sport University

Beijing, , China

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Peizhen Zhang

Role: CONTACT

01062989581

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Peizhen Zhang

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

EOCPEOVFOWIDMY

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.