Adapting an Intervention for Vaping in Young Veterans

NCT ID: NCT06196489

Last Updated: 2026-01-08

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 20 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-01-01
• Study Completion Date: 2026-06-30

Brief Summary

The objective of this proposal is to adapt an evidence-based combustible tobacco counseling intervention following an evidence-based process to include e-cigarette use and update its components for emerging adults (EA).

1. Examine factors related to e-cigarette use, barriers to cessation, and facilitators of use of cessation services among an EA population.

2. Beta-test an initial version of the intervention, delivered via video telehealth and telephone, to examine usability and acceptability.

Detailed Description

Use of electronic nicotine products (ENDS) has increased dramatically especially among young adults (EA- aged 18-30) and has been found to lead to immediate harmful health effects and increased addiction to combustible cigarette use. To date no research-tested interventions have been developed for helping people stop use of electronic nicotine products. Emerging adulthood is a developmental period that can lead to adoption of health risk behaviors.

This proposal aims to address nicotine addiction by adapting an evidence-based counseling cessation intervention developed by the American Cancer Society (ACS) for a general population of combustible tobacco smokers, but found to be effective in EA. We will test two methods of providing counseling to participants: video telehealth or telephone. Primary outcome: Compared to self-help guide only, at 3 month follow-up, we hypothesize that participants in either counseling arm will have higher rates as compared to self-help only control of 7-day abstinence from using any nicotine product.

This study fills a critical gap in ENDS research and will provide a model for further research into all-nicotine cessation in this vulnerable population.

Conditions

E Cigarette Use

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

telephone

Participants assigned to this group will receive the adapted intervention by telephone.

Group Type: EXPERIMENTAL

adapted vaping cessation intervention

Intervention Type: BEHAVIORAL

Behavioral intervention for vaping cessation

Video

Participants assigned to this group will receive the adapted intervention by video telehealth.

Group Type: EXPERIMENTAL

adapted vaping cessation intervention

Intervention Type: BEHAVIORAL

Behavioral intervention for vaping cessation

Interventions

adapted vaping cessation intervention

Behavioral intervention for vaping cessation

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• daily e-cigarette user for at least the past 6 months
• 18-30 years old
• willing to enroll in a program to quit nicotine use within 30 days
• owns smartphone or computer/tablet with camera and internet connectivity
• English speaker

Exclusion Criteria

• ICD-10 diagnosis of dementia
• current use of combustible tobacco products at least weekly

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 30 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of California

OTHER

Sponsor Role: collaborator

Veterans Medical Research Foundation

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Neal M Doran, PhD

Role: PRINCIPAL_INVESTIGATOR

Veterans Medical Research Foundation

Locations

Veterans Medical Research Foundation

San Diego, California, United States

Site Status: RECRUITING

Countries

United States

Central Contacts

Neal M Doran, PhD

Role: CONTACT

neal.doran@va.gov

858-552-8585

Facility Contacts

Neal Doran

Role: primary

neal.doran@va.gov

858-552-8585

References

Palmer AM, Tomko RL, Squeglia LM, Gray KM, Carpenter MJ, Smith TT, Dahne J, Toll BA, McClure EA. A pilot feasibility study of a behavioral intervention for nicotine vaping cessation among young adults delivered via telehealth. Drug Alcohol Depend. 2022 Mar 1;232:109311. doi: 10.1016/j.drugalcdep.2022.109311. Epub 2022 Jan 19.

Reference Type: BACKGROUND

PMID: 35123362 (View on PubMed)

Kinouani S, Leflot C, Vanderkam P, Auriacombe M, Langlois E, Tzourio C. Motivations for using electronic cigarettes in young adults: A systematic review. Subst Abus. 2020;41(3):315-322. doi: 10.1080/08897077.2019.1671937. Epub 2019 Oct 22.

Reference Type: BACKGROUND

PMID: 31638872 (View on PubMed)

Harrell PT, Brandon TH, Stark SE, Simmons VN, Barnett TE, Quinn GP, Chun S. Measuring vaping-related expectancies in young adults: Psychometric evaluation of the Electronic Nicotine Vaping Outcomes (ENVO) scale. Drug Alcohol Depend. 2023 May 1;246:109861. doi: 10.1016/j.drugalcdep.2023.109861. Epub 2023 Mar 29.

Reference Type: BACKGROUND

PMID: 37028105 (View on PubMed)

Cuccia AF, Patel M, Amato MS, Stephens DK, Yoon SN, Vallone DM. Quitting e-cigarettes: Quit attempts and quit intentions among youth and young adults. Prev Med Rep. 2021 Jan 5;21:101287. doi: 10.1016/j.pmedr.2020.101287. eCollection 2021 Mar.

Reference Type: BACKGROUND

PMID: 33489721 (View on PubMed)

Buu A, Hu YH, Wong SW, Lin HC. Comparing American college and noncollege young adults on e-cigarette use patterns including polysubstance use and reasons for using e-cigarettes. J Am Coll Health. 2020 Aug-Sep;68(6):610-616. doi: 10.1080/07448481.2019.1583662. Epub 2019 Mar 25.

Reference Type: BACKGROUND

PMID: 30908151 (View on PubMed)

Bandi P, Star J, Minihan AK, Patel M, Nargis N, Jemal A. Changes in E-Cigarette Use Among U.S. Adults, 2019-2021. Am J Prev Med. 2023 Aug;65(2):322-326. doi: 10.1016/j.amepre.2023.02.026. Epub 2023 Apr 18.

Reference Type: BACKGROUND

PMID: 37479423 (View on PubMed)

Other Identifiers

T31P1525

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

VeteransMRF

Identifier Type: -

Identifier Source: org_study_id