An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults

NCT ID: NCT06129123

Last Updated: 2026-01-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-01

Study Completion Date

2026-01-23

Brief Summary

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The goal of this intervention development and pilot clinical trial is to determine whether receiving the brief online intervention results in greater reductions in past 7-day e-cigarette use frequency and smoking susceptibility over an 8-week period compared to receiving the control condition in young adults who currently use e-cigarettes. Participants in the experimental condition will be asked to complete the 30-minute mobile-based program. Participants in the assessment-only control will be given the option to access the intervention after they complete their final survey at 8 weeks. All participants will complete our online surveys at baseline as well as 2-weeks, 4-weeks, and 8-weeks post-randomization. Researchers will compare outcomes among the intervention and control groups to determine the efficacy of the intervention.

Detailed Description

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Conditions

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E-cigarette Use

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Intervention

Participants will be asked to complete a 30-minute intervention that is accessible on a mobile device, delivered via a webpage, and personalized to their individual vaping behavior and beliefs (based on the baseline surveys). The intervention will contain personalized normative feedback (PNF), Motivational Enhancement (ME), and education.

Participants will complete assessments at baseline as well as 2-weeks, 4-weeks, and 8-weeks post randomization.

Group Type EXPERIMENTAL

Live Free From E-cigarettes

Intervention Type BEHAVIORAL

This is a 30-minute online educational program that focuses on providing information about e-cigarette and smoking social norms, harms of e-cigarettes and cigarettes, and ways to quit or reduce using e-cigarettes.

Waitlist Control

Participants will complete assessments at baseline as well as 2-weeks, 4-weeks, and 8-weeks post randomization. They will not receive the intervention during the active study phase, lasting 8 weeks. Participants will have the option to access the intervention once this active study phase is over.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Live Free From E-cigarettes

This is a 30-minute online educational program that focuses on providing information about e-cigarette and smoking social norms, harms of e-cigarettes and cigarettes, and ways to quit or reduce using e-cigarettes.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* be between the ages of 18 to 24
* be able to read English
* report vaping at least one day per week in the past month
* report no history of cigarette use at screening and baseline.

Exclusion Criteria

* reporting severe mental health, illicit drug use, or alcohol use disorder
* currently receiving nicotine cessation services
Minimum Eligible Age

18 Years

Maximum Eligible Age

24 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Southern California

OTHER

Sponsor Role lead

Responsible Party

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Denise Tran

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Denise D Tran, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Southern California

Locations

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University of Southern California

Los Angeles, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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I-Wen Contracts and Grants Coordinator

Role: CONTACT

310-918-0538

Facility Contacts

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Denise Tran

Role: primary

714-548-7785

References

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Tran DD, Davis JP, Buch K, Leventhal AM, Ewing SWF, Pedersen ER. A novel online vaping intervention and smoking prevention program for young adults who vape: protocol for a randomized controlled trial. Addict Sci Clin Pract. 2025 Apr 21;20(1):36. doi: 10.1186/s13722-025-00566-x.

Reference Type DERIVED
PMID: 40259422 (View on PubMed)

Other Identifiers

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UP-23-00005-AM001

Identifier Type: -

Identifier Source: org_study_id

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