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Post-Resuscitation Pneumothorax - Analysis of Incidence, Risk Factors and Outcome Relevance

NCT ID: NCT06182007

Last Updated: 2023-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

237 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-02-02

Study Completion Date

2022-12-31

Brief Summary

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In this retrospective study, the investigators seek to investigate the incidence of pneumothorax following possible risk factors, and elucidate its association with outcomes.

Detailed Description

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This is a retrospective analysis of routine data, collected by a single Emergency Medical System (EMS). Adult patients (≥18 years) hospitalised after Out-of-Hospital Cardiac Arrest (OHCA) who received chest compressions and underwent chest imaging within 12 hours after hospital admission were included.

Variables and outcomes ascertained are built up of the core elements of the latest version of the Utstein Resuscitation Registry Template for OHCA. This includes sex, age, aetiology of arrest, response times of the first emergency medical service team and emergency physician, witnessed cardiac arrest, bystander CPR/AED, arrest location, first monitored rhythm, defibrillation time, drugs given, reperfusion attempted and target temperature management. Additional variables studied were pre-existing health status represented by the Pre Emergency Status Assessment (PESA), history of lung disease, no-flow-time (time from collapse until initiation of CPR), use of a mechanical chest compression device and prehospital CPR duration.

The primary outcome is incidence of pneumothorax, secondary outcomes are survival to hospital discharge and favourable neurological condition at hospital discharge defined by a cerebral performance category (CPC) of 1 or 2.

Conditions

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Cardiac Arrest Pneumothorax Resuscitation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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No Pneumothorax

Patients with no pneumothorax reported from the first chest imaging after hospital admission.

Cardiopulmonary Resuscitation

Intervention Type PROCEDURE

Cardiopulmonary Resuscitation (Advanced Life Support) according to current guidelines

Pneumothorax

Patients with a pneumothorax reported from the first chest imaging after hospital admission.

Cardiopulmonary Resuscitation

Intervention Type PROCEDURE

Cardiopulmonary Resuscitation (Advanced Life Support) according to current guidelines

Interventions

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Cardiopulmonary Resuscitation

Cardiopulmonary Resuscitation (Advanced Life Support) according to current guidelines

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Hospitalized after out of hospital cardiac arrest
* Chest compressions received
* Chest imaging within the first 12 hours of admission

Exclusion Criteria

* Traumatic cardiac arrest
* Chest trauma/surgery/pneumothorax one month prior to cardiac arrest
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Auinger, Daniel MD

OTHER

Sponsor Role lead

Responsible Party

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Auinger, Daniel MD

MD

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Gerhard Prause, Prof.

Role: STUDY_DIRECTOR

Medical University of Graz

Locations

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Medical University of Graz

Graz, Styria, Austria

Site Status

Countries

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Austria

References

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Auinger D, Hotzer D, Zajic P, Orlob S, Heschl S, Fida S, Zoidl P, Honnef G, Friedl H, Smolle-Juttner FM, Prause G. Post-resuscitation pneumothorax: retrospective analysis of incidence, risk factors and outcome-relevance. Scand J Trauma Resusc Emerg Med. 2024 Sep 5;32(1):82. doi: 10.1186/s13049-024-01260-8.

Reference Type DERIVED
PMID: 39238051 (View on PubMed)

Other Identifiers

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PostCPRptx

Identifier Type: -

Identifier Source: org_study_id