Chronic Pain Following Thoracic Surgery

NCT ID: NCT01144845

Last Updated: 2011-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

702 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-04-30

Study Completion Date

2010-10-31

Brief Summary

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Pain that persists after the healing of a surgical wound has previously been described as an important, but often unrecognized clinical problem. Persistent postsurgical (chronic postoperative pain) is the consequence of either ongoing inflammation or more common neuropathic pain as a result of surgical damage to peripheral nerves.

Previous studies have shown that chronic pain is a frequent and serious complication following thoracic surgery. However, the prevalence of chronic pain following both thoracoscopy and anterior thoracotomy in patients with pulmonary malignancies is poorly characterized and the impact of this pain on patients' lives remains unclear. Thus, this study aims to investigate the prevalence of chronic pain following thoracoscopy or anterior thoracotomy, and the severity and impact of persistent post-surgical pain on daily life.

This study is working with several hypotheses: 1.) persistent postsurgical pain following lung cancer surgery is predominantly of neuropathic nature and the presence of neuropathic symptoms increases the severity of postsurgical pain and reduces the patient's quality of life, 2.) the prevalence of chronic pain is reduced over time, and 3.) less invasive thoracic surgical interventions reduces the risk of the development of chronic pain.

Detailed Description

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Conditions

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Pain, Postoperative

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Thoracic surgical patients

Patients with pulmonary malignancies

Thoracic surgery

Intervention Type PROCEDURE

Thoracoscopy or anterior thoracotomy

Interventions

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Thoracic surgery

Thoracoscopy or anterior thoracotomy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients who previously underwent thoracic surgery with lung resection from January 2000 to december 2009

Exclusion Criteria

* Death
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Aarhus

OTHER

Sponsor Role lead

Responsible Party

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Kasper Grosen

PhD fellow, Master of Health Sciences, RN

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kasper Grosen, PhDS, MHScS, RN

Role: PRINCIPAL_INVESTIGATOR

Department of Cardiothoracic and Vascular surgery, Aarhus University Hospital, Skejby, Denmark

Hans K Pilegaard, MD

Role: STUDY_DIRECTOR

Department of Cardiothoracic and Vascular surgery, Aarhus University Hospital, Skejby, Denmark

Vibeke Hjortdal, MD, Professor, DMSc, PhD

Role: STUDY_CHAIR

Department of Cardiothoracic and Vascular surgery, Aarhus University Hospital, Skejby, Denmark

Mogens P Jensen, MD, PhD

Role: STUDY_CHAIR

Department of Rheumatology, Aarhus University Hospital, Aarhus Hospital, Denmark

Locations

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Department of Cardiothoracic and Vascular surgery, Aarhus University Hospital, Skejby

Aarhus N, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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PTPS-18

Identifier Type: -

Identifier Source: org_study_id

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