Digital Versus Analog Pleural Drainage Following Pulmonary Resection

NCT ID: NCT01775657

Last Updated: 2022-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

176 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2021-12-01

Brief Summary

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This study will evaluate the impact of continuous, digital pulmonary air leak monitoring on the duration of pleural drainage after lung resection in patients with and without a pulmonary air leak on postoperative day 1.

Patients undergoing pulmonary resection who fit the inclusion criteria will be identified pre-operatively. Patients within two groups (air leak and no air leak) will be randomized to receive either the analogue system or the digital system. Both systems are approved for use in hospitals by Health Canada. There will be 88 patients in each air leak group.

Hypothesis: Continuous, quantitative monitoring of PAL following lung resection leads to an improvement in primary outcomes.

Detailed Description

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Conditions

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Pulmonary Air Leak Lobectomy Wedge Resection Segmentectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Air leak present - Analogue

Patients randomized to Pleur Evac (Analogue drainage) monitoring system, air leak present.

Group Type EXPERIMENTAL

Pleur Evac (Analogue drainage)

Intervention Type DEVICE

Air leak absent - Analogue (Pleur Evac)

Patients randomized to Pleur Evac (Analogue drainage) monitoring system, no air leak present

Group Type ACTIVE_COMPARATOR

Pleur Evac (Analogue drainage)

Intervention Type DEVICE

Air leak present - Digital (Thopaz)

Patients with an air leak present, randomized to Thopaz (digital drainage) monitoring system.

Group Type EXPERIMENTAL

Thopaz (Digital drainage)

Intervention Type DEVICE

Air leak absent - Digital (Thopaz)

Patients randomized to digital system, no air leak present.

Group Type ACTIVE_COMPARATOR

Thopaz (Digital drainage)

Intervention Type DEVICE

Interventions

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Thopaz (Digital drainage)

Intervention Type DEVICE

Pleur Evac (Analogue drainage)

Intervention Type DEVICE

Other Intervention Names

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Thopaz, Medela Switzerland Pleur Evac A-6002-08, Teleflex Inc, Research Triangle Park, NC, USA

Eligibility Criteria

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Inclusion Criteria

Elective pulmonary resection (i.e. wedge, segmentectomy, lobectomy, bilobectomy) for benign or neoplastic disease

Exclusion Criteria

1. Development of tension pneumothorax
2. Pneumonectomy
3. Patient no longer within planned randomization window
4. Plan to remove or removal of all chest drains within 36 hours of surgery
5. Inability to provide informed consent
6. Age \< 18 years
7. Patient was previously randomized following pulmonary resection
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ottawa Hospital Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sebastien Gilbert, MD

Role: PRINCIPAL_INVESTIGATOR

Ottawa Hospital Research Institute

Locations

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Ottawa Hospital, General Campus

Ottawa, Ontario, Canada

Site Status

Countries

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Canada

References

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Gilbert S, McGuire AL, Maghera S, Sundaresan SR, Seely AJ, Maziak DE, Shamji FM, Villeneuve PJ. Randomized trial of digital versus analog pleural drainage in patients with or without a pulmonary air leak after lung resection. J Thorac Cardiovasc Surg. 2015 Nov;150(5):1243-9. doi: 10.1016/j.jtcvs.2015.08.051. Epub 2015 Aug 28.

Reference Type DERIVED
PMID: 26409729 (View on PubMed)

Other Identifiers

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20120228-01H

Identifier Type: -

Identifier Source: org_study_id

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