Platelet-Rich and Concentrated Platelet-Poor Plasma to Reduce Air Leak Post-Lobectomy: A Randomized Controlled Trial
NCT ID: NCT00665912
Last Updated: 2017-03-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
204 participants
INTERVENTIONAL
2008-01-31
2010-11-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Prolonged Air Leak (PAL) Autologous Blood Patch Intervention Trial
NCT04954625
Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy
NCT06602661
A Phase II Prospective, Single Blinded, Randomized Trial of Hemopatch Compared to Standard Techniques to Achieve Air Leak Control After Complex Thoracic Surgical Procedures
NCT02364791
Digital Versus Analog Pleural Drainage Following Pulmonary Resection
NCT01775657
Stop Air Leak by Talc or Autologous Blood Patch Therapy
NCT06883188
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
1
Standard post-lobectomy wound care plus use of PRP and PPPc in the thoracic cavity.
Standard post-lobectomy wound care plus use of PRP and PPPc prepared by GPS and Plasmax respectively
GPS is used to create the platelet rich plasma (PRP). Plasmax is used to create the concentrated platelet-poor plasma (PPPc). Both PRP and PPPc will be used for wound care in the thoracic cavity post-lobectomy.
2
Standard post-lobectomy wound care in the thoracic cavity
Standard post-lobectomy wound care
Standard post-lobectomy wound care
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Standard post-lobectomy wound care plus use of PRP and PPPc prepared by GPS and Plasmax respectively
GPS is used to create the platelet rich plasma (PRP). Plasmax is used to create the concentrated platelet-poor plasma (PPPc). Both PRP and PPPc will be used for wound care in the thoracic cavity post-lobectomy.
Standard post-lobectomy wound care
Standard post-lobectomy wound care
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* Sleeve lobectomy
* Determination of unresectability (prior to the initiation of lobectomy)
* Wedge resection alone
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Western Ontario, Canada
OTHER
Zimmer Biomet
INDUSTRY
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Richard Inculet, MD, FRCSC, FACS
Role: PRINCIPAL_INVESTIGATOR
Western University, Canada
Darrin Payne, MD
Role: STUDY_CHAIR
Western University, Canada
Dalilah Fortin, MD
Role: STUDY_CHAIR
Western University, Canada
Richard Malthaner, MD
Role: STUDY_CHAIR
Western University, Canada
Robert Humphrey, MD
Role: STUDY_CHAIR
Western University, Canada
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of Western Ontario: Division of Thoracic Surgery
London, Ontario, Canada
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
BBI-004
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.