Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
20 participants
INTERVENTIONAL
2023-06-20
2025-06-30
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Abdominal Pressure Rise
Application of an abdominal weight and record of respiratory mechanics data, intra-abdominal pressure variation, Electrical Impedance Tomography data
Application of abdominal weight
Application of variable weight on the abdomen to reach a 5 mmHg increase in IAP
Interventions
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Application of abdominal weight
Application of variable weight on the abdomen to reach a 5 mmHg increase in IAP
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Need of PEEP trial
* Need of urinary catheter (used to measure IAP)
Exclusion Criteria
* Pacemaker or other metal device in thoracic region
* Contraindication to abdominal weight placement
* Surgical or traumatic incision on the abdomen
* Severe abdominal hypertension
* Esophageal diseases that counterindicate naso-gastric tube placement
* Severe hemodynamic instability (norepinephrine \> 0.1 mcg/kg/min; dobutamine or dopamine \> 5 mcg/kg/min; epinephrine every dosage)
* Severe obesity (BMI \> 35 kg/m2)
* Need of \> 7 kg weight to reach 5 mmHg IAP increase
18 Years
ALL
No
Sponsors
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University of Padova
OTHER
Responsible Party
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Paolo Persona
Medical Doctor, Principal Investigator
Locations
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Azienda Ospedaliera Università di Padova
Padua, , Italy
Countries
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Central Contacts
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Facility Contacts
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Paolo Persona, MD
Role: primary
References
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Pacchiarini G, Pettenuzzo T, Zarantonello F, Sella N, Lumetti G, Boscolo A, De Cassai A, Cammarota G, Persona P, Navalesi P; LOVE BEER Study Group. The "mechanical paradox" unveiled: a physiological study. Crit Care. 2025 May 16;29(1):194. doi: 10.1186/s13054-025-05385-9.
Other Identifiers
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AOP2978
Identifier Type: -
Identifier Source: org_study_id