MRI Analysis and Degenerative Spine

NCT ID: NCT06163300

Last Updated: 2024-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-01

Study Completion Date

2026-09-30

Brief Summary

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Analysis of MRI advanced techniques in degenerative spinal disease.

The main questions it aims to answer are:

* Can we assess microstructural integrity of compressed nerve roots in degenerative spinal disease
* What are the image biomarkers affected by disease
* How they evolve with disease progression and treatment

Detailed Description

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Conditions

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Spine Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Control

Healthy volunteers

MRI advanced techniques

Intervention Type DIAGNOSTIC_TEST

Participants will be submitted to MRI studies at diagnosis, during disease evolution and after treatment. Data collected will be analysed by two different neuroradiologists using advanced techniques.

Disease

Patients affected by disease

MRI advanced techniques

Intervention Type DIAGNOSTIC_TEST

Participants will be submitted to MRI studies at diagnosis, during disease evolution and after treatment. Data collected will be analysed by two different neuroradiologists using advanced techniques.

Interventions

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MRI advanced techniques

Participants will be submitted to MRI studies at diagnosis, during disease evolution and after treatment. Data collected will be analysed by two different neuroradiologists using advanced techniques.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age between 50 and 85 years
* Diagnosis of spinal disease by clinical and imagiological criteria
* More than 3 months duration of disease
* Ability to give consent
* Fluent portuguese speaker

Exclusion Criteria

* Previous spine surgery
* Spinal instability
* Neurological disease that might interfere with walking
* Known orthopedic conditions that causes significant gait impairment
* Dementia or development disorder with cognitive impairment
* Inability to give consent
Minimum Eligible Age

50 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universidade Nova de Lisboa

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hospital da Luz Setúbal

Setúbal, , Portugal

Site Status RECRUITING

Countries

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Portugal

Central Contacts

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Nuno A.R. Cristino, M.D.

Role: CONTACT

+351919484946

Facility Contacts

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Nuno Cristino, MD

Role: primary

+351919484946

Other Identifiers

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a319_b

Identifier Type: -

Identifier Source: org_study_id

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