Atherosclerotic Plaque Characterization

NCT ID: NCT00861653

Last Updated: 2014-04-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-10-31

Study Completion Date

2013-07-31

Brief Summary

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The purpose of this study is to utilize high-resolution CMR carotid imaging for the characterization of carotid wall volumes and plaque content in patients with clinical significant carotid atherosclerosis. Patients who are scheduled to undergo an imaging procedure will be recruited from the cath lab. Upon enrollment, blood samples conventional and genetic profiling will be collected. For patients undergoing a carotid endarterectomy, tissue from the carotid vessel will be collected during their procedure. Comparison of the MR images with tissue and/or blood samples will be made. Length of time in the study will be approximately 1 day. There will be no study-related patient follow-up.

Detailed Description

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Conditions

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Atherosclerosis

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age range \>17 years of age
* Surgical carotid artery disease
* Provide written informed consent and Authorization for Use/Disclosure of PHI

Exclusion Criteria

* History of carotid trauma
* History of middle or large vessel vasculitis
* Refusal to provide written informed consent and Authorization for
* Use/Disclosure of PHI
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Piedmont Healthcare

OTHER

Sponsor Role lead

Responsible Party

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Sarah Rinehart, MD

Principal Investigators

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Sarah Rinehart, MD

Role: PRINCIPAL_INVESTIGATOR

Piedmont Healthcare

Locations

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Piedmont Hospital

Atlanta, Georgia, United States

Site Status

Countries

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United States

Other Identifiers

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P06-31

Identifier Type: -

Identifier Source: org_study_id

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