Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI)

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

179 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-07-31

Study Completion Date

2008-06-30

Brief Summary

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The overall goal of this study is to use MRI to:

* Examine the relationship between known risk factors for cardiovascular disease and coronary artery wall thickness;
* Examine the relationship between coronary artery wall thickness and other markers of subclinical coronary atherosclerosis, such as carotid wall thickness and coronary calcium scores; and,
* Examine the feasibility of measuring the progression of coronary artery wall thickness over time in a subset of participants.

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Detailed Description

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Each enrolled participant will undergo MR Imaging of the coronary arteries in conjunction with their routine MESA follow-up visit. The MRI will last approximately 45-60 minutes

Conditions

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Coronary Arteriosclerosis Arteriosclerosis, Coronary Atherosclerosis, Coronary Coronary Artery Disease Coronary Atherosclerosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Interventions

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MR Imaging of the Coronary Arteries

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Prior enrollment in the MESA Study at the Hopkins MESA Field Center or the Northwestern University MESA Field Center
* Male or Female adult equal to or older than 45 years of age
* Willing/able to provide informed consent