Induction in the Dark

NCT ID: NCT06144177

Last Updated: 2025-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE4

Total Enrollment

240 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-04-16

Study Completion Date

2026-06-22

Brief Summary

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This study will enroll children ages 2-6 who are undergoing an elective outpatient surgical procedure under general anesthesia. They will be randomized to one of the following groups and assessed for preoperative anxiety, mask acceptance, and behavioral changes in the following week.

1. darkened room and star projector with parental presence;
2. preoperative midazolam 0.5 mg/kg by mouth and parental presence; or
3. parental presence alone.

Detailed Description

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Conditions

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Anesthesia Induction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Darkened room and star projector with parental presence

Subjects assigned to this arm, when in the operating room prior to the start of induction, the room will be darkened, and a star projector that lights up the ceiling and walls will be turned on. They will also have a parent in the room with them during induction of anesthesia.

Group Type ACTIVE_COMPARATOR

Dark with star projector

Intervention Type OTHER

When in the operating room prior to the start of induction, the room will be darkened, and a star projector that lights up the ceiling and walls will be turned on.

Parental Presence

Intervention Type OTHER

A parent or guardian will accompany the child into the OR and be present for the start of induction.

Preoperative midazolam 0.5 mg/kg po and parental presence

Subjects assigned to this arm will be given midazolam by mouth preoperatively, and will have a parent in the room with them during induction of anesthesia.

Group Type ACTIVE_COMPARATOR

Preoperative midazolam

Intervention Type DRUG

Midazolam by mouth preoperatively.

Parental Presence

Intervention Type OTHER

A parent or guardian will accompany the child into the OR and be present for the start of induction.

Parental presence alone

Subjects assigned to this arm will have a parent in the room with them during induction of anesthesia.

Group Type ACTIVE_COMPARATOR

Parental Presence

Intervention Type OTHER

A parent or guardian will accompany the child into the OR and be present for the start of induction.

Interventions

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Dark with star projector

When in the operating room prior to the start of induction, the room will be darkened, and a star projector that lights up the ceiling and walls will be turned on.

Intervention Type OTHER

Preoperative midazolam

Midazolam by mouth preoperatively.

Intervention Type DRUG

Parental Presence

A parent or guardian will accompany the child into the OR and be present for the start of induction.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age 2 to 6 years old
* American Society of Anesthesiologists physical status I-II
* Outpatient elective surgical procedures
* Undergoing general anesthesia
* Parent or guardian willing to be present during induction

Exclusion Criteria

* History of previous surgery
* Fear of the dark
* Contraindication to inhalational mask induction of general anesthesia such as allergy to inhalation medication, NPO violation, active nausea or vomiting, severe GERD, etc.
* Severe developmental delay
* Severe obvious, preoperative anxiety
* Patients currently using psychiatric medications
* Non-English speaking
Minimum Eligible Age

2 Years

Maximum Eligible Age

6 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of South Carolina

OTHER

Sponsor Role lead

Responsible Party

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Natalie Barnett

Associate Professor-Faculty

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Natalie Barnett, M.D.

Role: PRINCIPAL_INVESTIGATOR

Medical University of South Carolina

Locations

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Medical University of South Carolina

Charleston, South Carolina, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Haley Nitchie, MHA

Role: CONTACT

843-792-1869

Facility Contacts

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Haley Nitchie, MHA

Role: primary

843-792-1869

Other Identifiers

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Pro00132312

Identifier Type: -

Identifier Source: org_study_id

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