Vestibulo-Ocular Reflex Function in Individuals With Chronic Motion Sensitivity Cross-Sectional Study

NCT ID: NCT06128707

Last Updated: 2024-10-26

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 59 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-09-30
• Study Completion Date: 2024-02-01

Brief Summary

Chronic motion sensitivity refers to a sensation of unwellness caused by physical or discerned motion and has a prevalence of 28% in the general population and it is more common in women (27.3%) compared to men.

The investigators theorize that individuals with chronic motion sensitivity will have an impaired inner ear reflex and will be less physically active. Hence, the purpose of this study is to;

1. Determine whether the function of an inner ear reflex is different between young adults with/without chronic motion sensitivity

2. Assess relationships between reflex function and balance in young adults with/without CMS

3. Assess relationships between physical activity and balance in young adults with/without CMS.

Detailed Description

Chronic motion sensitivity (CMS), also known as motion sickness, refers to a sensation of unwellness caused by physical or discerned motion. CMS has a prevalence of 28% in the general population and it is more common in women (27.3%) compared to men.

Based on established evidence that individuals with chronic motion sensitivity demonstrate impaired postural stability with vestibular system impairment adjudged to be an inciting stimulus for chronic motion sensitivity, and individuals who practiced more physical and sporting activities have less motion sickness susceptibility than individuals who did not, the investigators theorize that individuals with chronic motion sensitivity will have an impaired inner ear reflex, causing them to be more reliant on other sensory systems like their muscles and joints, and their vision, we also theorize that individuals who are physically active will be less susceptible to chronic motion sensitivity.

The purpose of this study is to;

1. Determine whether the function of an inner ear reflex is different between young adults with/without chronic motion sensitivity

2. Assess relationships between reflex function and balance in young adults with/without CMS

3. Assess relationships between physical activity and balance in young adults with/without CMS.

Participants between the age of 20 and 40 with and without a self-reported history of chronic motion sensitivity (i.e, experiencing nauseousness and/or dizziness during while using various means of transportation such as, car, train, bus, boat, and airplane and/or, recreational fun-fair rides and/or when exposed to conflicting visual images). Participants will be excluded if they report a medical diagnosis of central nervous system disorder, impaired cervical spine range of motion, migraines, seizure disorder, vestibular dysfunction, or any musculoskeletal dysfunction that can limit their participation in the study.

Conditions

Motion Sickness

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Chronic Motion sensitivity group

Participants with a self-reported history of chronic motion sensitivity and who scored greater than or equal to the 30th percentile on the Motion sickness susceptibility questionnaire short form.

No interventions assigned to this group

Non-Chronic Motion sensitivity Group

Participants without a self-reported history of chronic motion sensitivity and who scored less than or equal to the 25th percentile on the Motion sickness susceptibility questionnaire short form.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Age 20-40
• With and without a history of CMS

Exclusion Criteria

• CNS disorder
• Impaired cervical spine ROM
• Migraines
• Seizures
• Vestibular dysfunction
• Musculoskeletal dysfunction
• Medications causing dizziness

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Loma Linda University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Loma Linda University

Loma Linda, California, United States

Countries

United States

Other Identifiers

IRB# 5230167

Identifier Type: -

Identifier Source: org_study_id