Diagnosis and Comprehensive Treatment of Mediastinal Interventional Technique

NCT ID: NCT06128681

Last Updated: 2025-01-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-12-01

Study Completion Date

2025-12-31

Brief Summary

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The goal of this observational study is to learn abou Whether patients undergoing mediastinal disease diagnosis and combined treatment with intrapacial ultrasound-guided mediastinal opening techniques have greater clinical benefit.

The participants were physically ill. The main questions it aims to answer are:

* Whether the mediastinal ultrasound-guided mediastinal opening technique is more beneficial for the diagnosis of benign or malignant mediastinal diseases.
* Does the mediastinal ultrasound-guided mediastinal opening technique benefit the patient by ablating mediastinal masses using freezing, laser, or other means.

Mediastinal diseases were diagnosed by lymph node biopsy combined with NGS, ROSE and other techniques using transairway ultrasound-guided mediastinal opening technique. Ablation of mediastinal malignancies is performed using techniques such as freezing or laser.

Researchers will compare the experimental group with mediastinal opening and the control group without mediastinal opening to see if Mediastinal open technique benefits patients.

Detailed Description

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Conditions

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Mediastinal Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Mediastinal open group

Mediastinal opening technique was performed with intraairway ultrasound guidance

Intraairway ultrasound-guided mediastinal opening technique

Intervention Type PROCEDURE

Mediastinal intervention for patients with mediastinal imaging abnormalities is performed under general anesthesia to obtain biopsy specimens for detection or elimination of mediastinal masses

Non-mediastinal open group

Diagnosis and treatment are routinely performed without any manipulation of the mediastinum

No interventions assigned to this group

Interventions

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Intraairway ultrasound-guided mediastinal opening technique

Mediastinal intervention for patients with mediastinal imaging abnormalities is performed under general anesthesia to obtain biopsy specimens for detection or elimination of mediastinal masses

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Radiographic abnormalities of mediastinum
* Can tolerate general anesthesia
* Can tolerate bronchoscopy and has the condition to have mediastinal biopsy and treatment

Exclusion Criteria

* Imaging or other tests can make a definitive diagnosis
* Cannot tolerate general anesthesia or tracheoscopic surgery
* Patients cannot sign informed consent forms
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dan Liu

OTHER

Sponsor Role lead

Responsible Party

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Dan Liu

Doctor of Medicine

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Tianjin Medical University General Hospital

Tianjin, , China

Site Status RECRUITING

Countries

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China

Facility Contacts

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Dan Liu

Role: primary

Jing Feng

Role: backup

Dan Liu

Role: backup

Other Identifiers

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Tianjinzyyhxkld

Identifier Type: -

Identifier Source: org_study_id

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