The Application of the New Magnetic Resonance UTE Technique in Thoracic Lesions

NCT ID: NCT05998707

Last Updated: 2023-08-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-07-01

Study Completion Date

2024-06-13

Brief Summary

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Quantitative characteristic values of lung lesions were obtained by UTE technique, so as to make qualitative diagnosis of benign and malignant lesions. And to explore the clinical feasibility of CT-like technology - high resolution ZTE technology in the diagnosis of pulmonary diseases.

Detailed Description

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Ultrashort echo time (UTE) sequence can obtain data from T2\* for lung imaging before T2\* decays in lung parenchyma with extremely short echo time, which makes up for the defect that conventional MRI cannot clearly display short T2 tissue imaging, and can provide more supplementary information for lung CT scan. There has been a lot of research progress in the evaluation of neonatal lung disease, chronic obstructive airway disease and pneumonia. The 3D UTE sequence developed on this basis has made great progress in improving the resolution, signal-to-noise ratio and shortening the scanning time of lung MR Images, and has successfully obtained submillimeter high-resolution images. The purpose of this study was to explore the value of MRI ultra-short echo technology in the qualitative diagnosis of benign and malignant lung lesions, and to explore the clinical application of CT-like technology - high resolution ZTE technology in the lung.

Conditions

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Lung Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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benign group

benign lesions in the lung

No interventions assigned to this group

malignant group

malignant tumor in the lung

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Age ≥18 years old;
2. There are lung lesions, and the solid component is ≥6mm;
3. Chest CT plain scan or /+ enhanced examination within 4 weeks.

Exclusion Criteria

1. There are metal implants in the corresponding parts of the chest;
2. MRI contrast agent allergy;
3. Claustrophobia;
4. Pregnant women;
5. High fever;
6. Respiratory failure;
7. Lung lesion biopsy within 4 weeks prior to examination.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fifth Affiliated Hospital, Sun Yat-Sen University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Shaolin Li

Role: STUDY_DIRECTOR

Fifth Affiliated Hospital, Sun Yat-Sen University

Locations

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Radiography department

Zhuhai, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Xiaojun Chen

Role: CONTACT

+8615820587112

Facility Contacts

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Xiaojun Chen

Role: primary

+8615820587112

Other Identifiers

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ZDWY.FSK.024

Identifier Type: -

Identifier Source: org_study_id

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