Protocol for a Feasibility Cluster Randomised Controlled Trial of a Home-based Depression Care for Older People Delivered by Lay Providers in Nigeria

NCT ID: NCT06125899

Last Updated: 2023-11-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

110 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-02-29

Study Completion Date

2025-07-31

Brief Summary

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The aim of this hybrid (Effectiveness-Implementation) cluster randomised controlled clinical trial is to test the feasibility of implementing an age-appropriate electronic version of the WHO Mental Health Gap Action Programme Intervention Guide (emhGAP-Age) in routine home-based care of older Nigerians with depression. The main questions it aims to answer are:

1. Whether the emhGAP-Age demonstrate sufficient signals of effectiveness in the identification and home management of late life depression to permit for further exploration in a fully powered clinical trial?
2. What are the logistical, programmatic, and operational requirements for a home-delivered emhGAP-Age in a sample of older people with depression in Nigeria? Consenting older participants with depression in the intervention arm will receive treatment based on emhGAP-Age which consists of;

* Adapted electronic generic version of the WHO Mental Health Gap Action Programme Intervention Guide (emhGAP-IG)
* Adapted Problem-Solving Therapy (PST-PC)
* Support/supervision of providers
* Links to social support resources. Researchers will compare with treatment based on the basic specification in the generic emhGAP-IG (consisting of basic psychoeducation and stress reduction) for effects on depression remission.

Detailed Description

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Conditions

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Depression in Old Age

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Age emhGAP-IG

* Adapted emhGAP-IG;
* Adapted Problem-Solving Therapy (PST-PC)
* Support/supervision of lay providers
* Links to social support resources.

Group Type EXPERIMENTAL

emhGAP-Age

Intervention Type BEHAVIORAL

* Adapted emhGAP-IG;
* Adapted Problem-Solving Therapy (PST-PC)
* Support/supervision of lay providers
* Links to social support resources.

Generic emhGAP-IG

Psychoeducation and stress reduction

Group Type ACTIVE_COMPARATOR

emhGAP-Age

Intervention Type BEHAVIORAL

* Adapted emhGAP-IG;
* Adapted Problem-Solving Therapy (PST-PC)
* Support/supervision of lay providers
* Links to social support resources.

Interventions

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emhGAP-Age

* Adapted emhGAP-IG;
* Adapted Problem-Solving Therapy (PST-PC)
* Support/supervision of lay providers
* Links to social support resources.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. Age ≥ 60 years,
2. PHQ-9 score of ≥11 during routine consultation

Exclusion Criteria

1. Severe co-morbidity requiring urgent attention.
2. Severe cognitive impairment/dementia (Community Screening Instruments for Dementia score≤ 20) .
3. Active suicidal intention.
4. Evidence of bipolar/psychosis/severe substance use disorders.
5. Planning to move out of the study catchment area within 6 months.
6. Refusing/lacking capacity to consent/accent
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Ibadan

OTHER

Sponsor Role lead

Responsible Party

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Akin Ojagbemi

Senior Lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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220684/Z/20/Z

Identifier Type: -

Identifier Source: org_study_id

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