Improving Depression Care for Elders: Coordinating Center

NCT ID: NCT01561105

Last Updated: 2012-03-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

1801 participants

Study Classification

INTERVENTIONAL

Study Start Date

1999-01-31

Study Completion Date

2004-06-30

Brief Summary

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Purpose: To determine the effectiveness of the Improving Mood-Promoting Access to Collaborative Treatment(IMPACT) collaborative care management program for late-life depression.

Detailed Description

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This study tested an organized method of delivering care for late life depression in primary care. Specifically, the investigators evaluated the effectiveness of this intervention as compared to 'care as usual'. The investigators studied the effect of the intervention on clinical outcomes such as depressive symptoms, functional status, health related quality of life. They also determined the cost-effectiveness of the intervention compared to care as usual.

Conditions

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Major Depression Dysthymic Disorder Both Major Depression and Dysthymic Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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IMPACT

Group Type EXPERIMENTAL

IMPACT

Intervention Type OTHER

IMPACT is a collaborative care management program for late-life depression

Care as Usual

Patients received all depression care available to them as part of care as usual in the participating primary care clinics.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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IMPACT

IMPACT is a collaborative care management program for late-life depression

Intervention Type OTHER

Other Intervention Names

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Improving Mood-Promoting Access to Collaborative Treatment

Eligibility Criteria

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Inclusion Criteria

* Major depression or dysthymia as diagnosed by a structured diagnostic interview.
* Patient plans to receive primary care at the study clinic for the next year.

Exclusion Criteria

* Age under 60.
* Current symptoms or history of psychosis or mania as determined by structured diagnostic interview.
* Cognitive impairment as defined by a score less than 23 on a Mini Mental Status Examination.
* Terminal illness - defined as having a life expectancy of less than 6 months.
* Active alcohol abuse as determined by a screening interview.
* High suicide risk as determined by current plan for suicide or a history of more than 3 prior suicide attempts in the past 10 years.
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The John A. Hartford Foundation

OTHER

Sponsor Role collaborator

California HealthCare Foundation

OTHER

Sponsor Role collaborator

Hogg Foundation

UNKNOWN

Sponsor Role collaborator

Robert Wood Johnson Foundation

OTHER

Sponsor Role collaborator

University of California, Los Angeles

OTHER

Sponsor Role lead

Responsible Party

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Jurgen Unutzer, MD, MPH

Professor and Vice-Chair of Psychiatry, Psychiatry and Behavioral Sciences

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jurgen Unutzer, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

University of Washington

References

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Unutzer J, Katon W, Callahan CM, Williams JW Jr, Hunkeler E, Harpole L, Hoffing M, Della Penna RD, Noel PH, Lin EH, Arean PA, Hegel MT, Tang L, Belin TR, Oishi S, Langston C; IMPACT Investigators. Improving Mood-Promoting Access to Collaborative Treatment. Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial. JAMA. 2002 Dec 11;288(22):2836-45. doi: 10.1001/jama.288.22.2836.

Reference Type RESULT
PMID: 12472325 (View on PubMed)

Stewart JC, Perkins AJ, Callahan CM. Effect of collaborative care for depression on risk of cardiovascular events: data from the IMPACT randomized controlled trial. Psychosom Med. 2014 Jan;76(1):29-37. doi: 10.1097/PSY.0000000000000022. Epub 2013 Dec 23.

Reference Type DERIVED
PMID: 24367124 (View on PubMed)

Other Identifiers

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JAHF 98297

Identifier Type: -

Identifier Source: org_study_id

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