Micronutrient Levels and Nutritional Status in Critical Illness
NCT ID: NCT06119711
Last Updated: 2024-11-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
79 participants
OBSERVATIONAL
2023-05-08
2023-10-03
Brief Summary
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Objective:
Main: Assess nutrition-related biomarkers in plasma and urine samples at ICU admission
Secondary:
Identify the number of micronutrient deficiencies at ICU admission Compare biomarker profile and dietary intake of short and long-stay ICU patients at baseline Compare subjective dietary intake, nutritional status and muscle thickness between patients with and without micronutrient deficiencies at baseline Study design: Observational study
Study population: Adult patients admitted to the ICU. Two groups will be recruited: patients with a short length of stay (\<48 hours) and patients with a longer length of stay (≥48 hours).
Main study parameters: Biomarker status in blood and urine at ICU admission.
Nature and extent of the burden and risks associated with participation, benefit and group relatedness: In addition to standard care ICU treatment, the following measurements will be performed:
* Within 24 hours after admission blood and urine samples will be collected from existing venous line and urinary catheter
* Within 72 hours an ultrasound measurement of the upper leg will be performed.
* During ICU stay, when the patient is capable to do so, they will be asked to complete a retrospective dietary intake assessment.
The risks and negative effects of these tests are limited. However, this study asks for a time investment and physical and mental effort of the patients.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Short stay
Patients admitted to the ICU with a need for mechanical ventilation of less than 48 hours
No intervention
No intervention
Long stay
Patients admitted to the ICU with a need for mechanical ventilation of 48 hours or more
No intervention
No intervention
Interventions
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No intervention
No intervention
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Comorbidity highly affecting gut absorption (e.g. post-bariatric surgery)
18 Years
ALL
No
Sponsors
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University of Groningen
OTHER
Frisius Medisch Centrum
OTHER
Responsible Party
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Lise Beumeler
Principal Investigator
Locations
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Medical Centre Leeuwarden
Leeuwarden, , Netherlands
Countries
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Other Identifiers
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NL83298.099.22
Identifier Type: -
Identifier Source: org_study_id
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