Characterization of Anti-HLA Alloimmunization After Pulmonary Valve Homograft Insertion
NCT ID: NCT06113224
Last Updated: 2023-11-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
53 participants
INTERVENTIONAL
2023-12-31
2027-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
OTHER
NONE
Study Groups
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Control patients
Patients with an indication for cardiac surgery with extracorporeal circulation but without homograft
Blood collection T0
2 blood samples will be taken in addition to the pre-operative check-up.
Blood collection 6 months
1 blood sample will be taken 6 months after surgery.
Lung homograft patients
patients requiring lung homograft implantation
Blood collection T0
2 blood samples will be taken in addition to the pre-operative check-up.
Blood collection 6 months
1 blood sample will be taken 6 months after surgery.
Interventions
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Blood collection T0
2 blood samples will be taken in addition to the pre-operative check-up.
Blood collection 6 months
1 blood sample will be taken 6 months after surgery.
Eligibility Criteria
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Inclusion Criteria
* Patient aged 14 or over
* Signature of consent by adult patients/parents/guardians and assent by children
* Patientsreceiving a cardiac surgery with extracorporeal circulation and without lung homograft
Exclusion Criteria
* Pregnant women or childbirth within the last 6 months
* Transfusion during the surgery or within the last 6 months
* Patient with DSAs detected before the surgery
* Patient with anti-HLA antibodies (non-DSAs) detected before the surgery
14 Years
ALL
No
Sponsors
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Assistance Publique Hopitaux De Marseille
OTHER
Responsible Party
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Central Contacts
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Other Identifiers
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RCAPHM22_0448
Identifier Type: -
Identifier Source: org_study_id
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