Lidocaine in the Prevention of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation
NCT ID: NCT06107543
Last Updated: 2024-06-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
94 participants
OBSERVATIONAL
2023-12-01
2024-06-22
Brief Summary
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In this study, the researchers aimed to compare the results of using intravenous lidocaine and nebulized lidocaine to suppress the hemodynamic response caused by laryngoscopy and endotracheal intubation retrospectively.
Researchers' hypothesis; Nebulized lidocaine administration is more effective than intravenous lidocaine administration in suppressing the hemodynamic response due to laryngoscopy and endotracheal intubation in patients under general anesthesia.
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Detailed Description
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Nebulized lidocaine in the researchers' clinic; it is administered by adding 2% lidocaine + physiological saline to a nebulizer and inhaling for 3-5 minutes in the presence of 4-6 liters/minute of oxygen.
Preoperative examination forms and intraoperative follow-up forms of the patients included in the study will be examined by the researchers. The dose of lidocaine applied and the method of administration will be recorded. In addition, the agents used in anesthesia induction (fentanyl, propofol, rocuronium bromide, etc.) and the hemodynamic changes of the patients (heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure,oxygen saturation) will be recorded.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Intravenous lidocaine
Patients who received lidocaine intravenously before induction of anesthesia will be considered in this group.
Iv Lidocaine
Intravenous %2 lidocaine was administered before induction of anesthesia.
Nebulized lidocaine
Patients who received lidocaine by inhalation with a nebulizer before induction of anesthesia will be considered in this group.
Nebulized Lidocaine
Before induction of anesthesia, 2% lidocaine + physiological saline was added to a nebulizer and inhaled for 3-5 minutes in the presence of 4-6 liters/minute of oxygen.
Interventions
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Nebulized Lidocaine
Before induction of anesthesia, 2% lidocaine + physiological saline was added to a nebulizer and inhaled for 3-5 minutes in the presence of 4-6 liters/minute of oxygen.
Iv Lidocaine
Intravenous %2 lidocaine was administered before induction of anesthesia.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Patients who are not operated under general anesthesia
18 Years
80 Years
ALL
Yes
Sponsors
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Derince Training and Research Hospital
OTHER
Responsible Party
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Emine Atlı
MD, Anesthesiology and Reanimation
Locations
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Derince Training and Research Hospital
Kocaeli, , Turkey (Türkiye)
Countries
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References
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Baronia AK, Singh PK, Maheshwari A, Jain VK, Mittal P, Pant KC. Inhaled lidocaine for prevention of hemodynamic changes in laryngoscopy and intubation. J Neurosurg Anesthesiol. 1992 Jul;4(3):154-9. doi: 10.1097/00008506-199207000-00002.
Sklar BZ, Lurie S, Ezri T, Krichelli D, Savir I, Soroker D. Lidocaine inhalation attenuates the circulatory response to laryngoscopy and endotracheal intubation. J Clin Anesth. 1992 Sep-Oct;4(5):382-5. doi: 10.1016/0952-8180(92)90160-3.
Other Identifiers
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DerinceTRH-EAtli-001
Identifier Type: -
Identifier Source: org_study_id
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