Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
60 participants
INTERVENTIONAL
2016-06-30
2016-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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dexmedetomidine
0.5 mcg/kg dexmedetomidine in 20 ml normal saline will be infused in 5 minutes before intubation
Dexmedetomidine
Esmolol
0.5 mg/kg esmolol in 20 ml normal saline will be infused in 5 minutes before intubation
Esmolol
Placebo
20 ml normal saline infused in 5 minutes before intubation
Placebo
normal saline
Interventions
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Dexmedetomidine
Esmolol
Placebo
normal saline
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Morbid obesity (BMI\>30)
* Advanced systemic disease
* Hypoalbumiemia
* beta-blocker usage
* Anticipated difficult ventilation and/or intubation
18 Years
65 Years
ALL
No
Sponsors
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Ufuk University
OTHER
Responsible Party
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Perihan Ekmekçi
Associate Professor
Locations
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Ufuk University Hospital
Ankara, , Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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References
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Yallapragada SV, Vidadala KS, Vemuri NN, Shaik MS. Comparison of the efficacy of dexmedetomidine with that of esmolol in attenuating laryngoscopic and intubation response after rapid sequence induction. Anesth Essays Res. 2014 Sep-Dec;8(3):383-7. doi: 10.4103/0259-1162.143154.
Other Identifiers
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RespToIntubation
Identifier Type: -
Identifier Source: org_study_id
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