Effect of Cystocele Repair With Trans Obturator Tape VS. Trans Obturator Tape Alone on Stress Urinary Incontinence.

NCT ID: NCT06044987

Last Updated: 2025-02-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

98 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-09-01

Study Completion Date

2022-09-01

Brief Summary

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The goal of this interventional study is to compare the effect of Concurrent cystocele repair and trans obturator tape (TOT) and TOT alone in a sample of Iraqi Female participants with diagnosed stress urinary incontinence and cystocele. The main questions to answer are:

1-What are the effects of the tested Interventions on the outcomes measured by The Pelvic Organ Prolapse Quantification (POP-Q) System?

1. What are the effects of the tested Interventions on the degree of pelvic organ prolapse?
2. What are the effects of the tested Interventions on the frequency, severity, and effect of Stress urinary incontinence on the quality of life of the patients?
3. What are the effects of the tested Interventions on the impact of lower urinary tract symptoms on the quality of the patient's life?

Female Patients diagnosed with SUI indicated for intervention were divided into 2 groups

Group I: (n=49) offered TOT alone

Group II: (n=49) offered concurrent TOT and Cystocele Repair

Patients were then followed up and evaluated using The Pelvic Organ Prolapse Quantification (POP-Q) System, The International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF), and the King Health Questionnaire (KHQ). The efficacy of both procedures and their impact on SUI and quality of life was measured.

Detailed Description

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Conditions

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Stress Urinary Incontinence

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Group I (TOT alone)

49 Female Patients diagnosed with Stress urinary incontinence and cystocele and offered repair by Trans obturator tape procedure

Group Type ACTIVE_COMPARATOR

Trans Obturator Tape Procedure (TOT)

Intervention Type PROCEDURE

Done under Spinal anesthesia in the dorsal lithotomy position.

Group II (TOT+ Cystocele Repair)

49 Female Patients diagnosed with Stress urinary incontinence and cystocele and offered repair by Trans obturator tape procedure concurrently with cystocele repair.

Group Type EXPERIMENTAL

Trans Obturator Tape Procedure (TOT)

Intervention Type PROCEDURE

Done under Spinal anesthesia in the dorsal lithotomy position.

Cystocele Repair

Intervention Type PROCEDURE

Done under Spinal anesthesia in the dorsal lithotomy position..

Interventions

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Trans Obturator Tape Procedure (TOT)

Done under Spinal anesthesia in the dorsal lithotomy position.

Intervention Type PROCEDURE

Cystocele Repair

Done under Spinal anesthesia in the dorsal lithotomy position..

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Female patients.
* Pure stress and/or stress-predominant mixed urinary incontinence (MUI) associated with cystocele.
* Had not undergone a previous SUI surgery.
* BMI less than 35 kg/m2

Exclusion Criteria

* Patients out of the age limit.
* Patients refused to participate in the study.
* Severe comorbid disease (heart failure HYHA class II and above, etc.).
* Patients with a previous surgical history of transvaginal mesh.
* Patients suffering detrusor overactivity.
* Patients diagnosed with the female genital system or urinary bladder Malignancies.
* Patients diagnosed with the presence of neurological disorders that caused voiding dysfunction.
Minimum Eligible Age

40 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Al-Sadr Teaching Hospital

OTHER_GOV

Sponsor Role collaborator

Al-Mustafa University College

OTHER

Sponsor Role lead

Responsible Party

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Hayder Adnan Fawzi

Assistant Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hayder Adnan Fawzi, Ph.D

Role: STUDY_CHAIR

Al-Mustafa University College

Thaer Saleh Sabor Al-Omary, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Al-Sadr Teaching Hospital

Locations

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Al-Sadr Teaching Hospital

Amarah, Maysan, Iraq

Site Status

Countries

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Iraq

Other Identifiers

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A-202301

Identifier Type: -

Identifier Source: org_study_id

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