Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
40 participants
INTERVENTIONAL
2023-03-01
2025-12-31
Brief Summary
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Detailed Description
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Component 1: The CRT programme used in this study is the Computerised Interactive Remediation of Cognition- Training for Schizophrenia (CIRCuiTS). CIRCuiTS is a web-based CRT programme which targets metacognition, specifically strategy use, in addition to massed practice of cognitive functions (attention, memory and executive functioning). Collaborative goal setting related to real-world tasks are integral to the programme with the programme tasks and exercises increasing in difficulty in response to the participant's performance and progress. This will be the primary focus of 1:1 therapy for the first 7 weeks with remote practice sessions occurring between therapy visits. After 7 weeks remote practice will continue and the focus of in-person therapy sessions will bridge to social recovery therapy as detailed below.
Component 2: Social recovery therapy (SRT) focuses on addressing barriers to individuals interacting in their social environment e.g., social anxiety. It is informed by cognitive behavioural theory and addresses individual goals. SRT follows an established protocol. In summary, this consists of therapy delivered in three stages. Stage one will include engagement and formulation with the purpose of identifying a problem list and establishing a therapeutic relationship. Stage two will include preparing for new activities with identification of pathways to activity and collaboration with community stakeholders. Stage three will include engagement in new activities using behavioural experiments to promote social activity. This is the primary focus of in-person therapy sessions from week 8 to 15 alongside remote practice of the CRT programme.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Intervention
15 sessions of the combined cognitive remediation training and social recovery therapy intervention.
CRESTR Intervention
15 1-hour sessions of CRT + SRT
Control
15 sessions of social recovery therapy alone.
CRESTR Control
15 1-hour sessions of SRT alone
Interventions
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CRESTR Intervention
15 1-hour sessions of CRT + SRT
CRESTR Control
15 1-hour sessions of SRT alone
Eligibility Criteria
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Inclusion Criteria
* Within the first 5 years of a diagnosed psychotic disorder
* Community based and clinically stable
* Ability to give informed consent
Exclusion Criteria
* IQ\< 70
* History of head injury with loss of consciousness \> 5-minute duration
18 Years
60 Years
ALL
Yes
Sponsors
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Health Service Executive, Ireland
OTHER
Health Research Board, Ireland
OTHER
National University of Ireland, Galway, Ireland
OTHER
Responsible Party
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Gary Donohoe
Professor Gary Donohoe
Locations
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HSE Early Intervention in Psychosis Service, Cork
Cork, , Ireland
DETECT Early Intervention in Psychosis Service
Dublin, , Ireland
Adult Mental Health Service, University Hospital Galway
Galway, , Ireland
HSE Early Intervention in Psychosis Service, Meath
Navan, , Ireland
HSE Early Intervention in Psychosis Service, Sligo
Sligo, , Ireland
Countries
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Central Contacts
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Facility Contacts
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Mary Clarke, Prof.
Role: primary
Other Identifiers
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NUIRELAND2
Identifier Type: -
Identifier Source: org_study_id
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