Conservative Treatment or Resuturing Among Women With Perineal Wound Dehiscence After Vaginal Labour

NCT ID: NCT06026423

Last Updated: 2023-09-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-15

Study Completion Date

2026-09-01

Brief Summary

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The goal of this observational study is to make us more aware of the short and long-term outcomes for women having an uncomplicated healing process after a rupture or birth cut in the perineum after giving birth in relation to a healing process with a dehisced wound treated with conservative management or secondary suturing.

Participants will be asked to do

* A gynecological examination at one month after birth and 9-12 months after birth.
* Have a picture taken of the healing process
* Answer a questionnaire at one month, three months, and 9-12 months after birth

Detailed Description

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The best way to manage perineal wound dehiscence after childbirth is unknown. Currently, there is no agreed best practice recommendation for managing perineal wound dehiscence due to a lack of evidence comparing conservative management with secondary suturing. Therefore, studies are urgently needed to compare the benefits and risks of both treatments. This study has the potential to significantly impact women´s health for those suffering from perineal wound dehiscence.

The investigators want to include 100 women who have had a primary repair of a second-degree tear or episiotomy with a normal/uncomplicated healing process, 100 women with a second-degree tear or episiotomy identified with a dehisced wound treated with secondary resuturing, and 100 women with a second-degree tear or episiotomy identified with a dehisced wound treated with conservative management.

All women who meet the inclusion criteria are recommended the same treatment and follow-up as currently present as standard care at the four hospitals that the investigators are recruiting from. The study deviates from the standard of care by offering two extra clinical examinations, one questionnaire evaluation without clinical examination, and a follow-up with pictures of the perineal tear healing process.

Conditions

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Dehiscence Wound Secondary Perineal Tear Episiotomy; Dehiscence

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Normal/uncomplicated healing process

100 women with a second-degree tear or episiotomy primarily sutured after labor: identified with a normal/uncomplicated healing process

Clinical examination and pictures

Intervention Type OTHER

A clinical examination is needed to assess the healing process for the three groups. After assessing the healing process, we will take pictures of the tear for documentation.

Questionnaire

Intervention Type OTHER

The participant will answer questions, serving as a baseline questionnaire, when arriving at the clinical examination one month post-partum. At three and 9-12 months post-postpartum, they will receive another questionnaire. The questionnaire will consist of validated questions regarding body image, pain, Urogynecological problems as symptoms of prolapse, urinary and anal incontinence, and questions about sexual problems.

Dehisced wound treated with secondary resuturing

100 women with a second-degree tear or episiotomy: identified with a dehisced wound treated with secondary resuturing

Clinical examination and pictures

Intervention Type OTHER

A clinical examination is needed to assess the healing process for the three groups. After assessing the healing process, we will take pictures of the tear for documentation.

Questionnaire

Intervention Type OTHER

The participant will answer questions, serving as a baseline questionnaire, when arriving at the clinical examination one month post-partum. At three and 9-12 months post-postpartum, they will receive another questionnaire. The questionnaire will consist of validated questions regarding body image, pain, Urogynecological problems as symptoms of prolapse, urinary and anal incontinence, and questions about sexual problems.

Dehisced wound treated with conservative management

100 women with a second-degree tear or episiotomy: identified with a dehisced wound treated with conservative management

Clinical examination and pictures

Intervention Type OTHER

A clinical examination is needed to assess the healing process for the three groups. After assessing the healing process, we will take pictures of the tear for documentation.

Questionnaire

Intervention Type OTHER

The participant will answer questions, serving as a baseline questionnaire, when arriving at the clinical examination one month post-partum. At three and 9-12 months post-postpartum, they will receive another questionnaire. The questionnaire will consist of validated questions regarding body image, pain, Urogynecological problems as symptoms of prolapse, urinary and anal incontinence, and questions about sexual problems.

Interventions

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Clinical examination and pictures

A clinical examination is needed to assess the healing process for the three groups. After assessing the healing process, we will take pictures of the tear for documentation.

Intervention Type OTHER

Questionnaire

The participant will answer questions, serving as a baseline questionnaire, when arriving at the clinical examination one month post-partum. At three and 9-12 months post-postpartum, they will receive another questionnaire. The questionnaire will consist of validated questions regarding body image, pain, Urogynecological problems as symptoms of prolapse, urinary and anal incontinence, and questions about sexual problems.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Women with a vaginal delivery who have had a primary repair of a second-degree perineal tear or episiotomy
* At least 18 years old
* Able to understand, read and speak Danish or English
* Able to give informed consent

Exclusion Criteria

* None, first, third- and fourth-degree tear
* Cesarean Section
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Herlev Hospital

OTHER

Sponsor Role lead

Responsible Party

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Hanna Jangö

Staff specialist, Ph.D., Associated professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hanna M. Jangö, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Copenhagen University Hospital - Herlev and Gentofte

Locations

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Department of Obstetrics and Gynaecology, Copenhagen University Hospital - Herlev and Gentofte

Herlev, , Denmark

Site Status RECRUITING

Countries

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Denmark

Central Contacts

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Lærke V. Moestrup, PhD student

Role: CONTACT

+45 21351767

Hanna M. Jangö, MD, PhD

Role: CONTACT

+45 38381612

Facility Contacts

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Hanna M. Jangö, MD, PhD, Associate Professor

Role: primary

+4538681612

Other Identifiers

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H-23022460

Identifier Type: -

Identifier Source: org_study_id

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