Disease Characteristics of IR-CAD: a Case-control Study
NCT06007248 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2025-11-19
Summary
The present case-control study is designed to investigate the disease characteristics of IR-CAD by comparing the demographics, clinical features, lab results, imaging findings, and prior treatment between 20 patients with IR-CAD and 10 patients with AS-CAD.
Conditions
- Coronary Artery Disease
- Coronary Artery Stenosis
- Coronary Artery Restenosis
- Coronary Artery Disease Progression
- Inflammation
- Inflammatory Disease
- Inflammation Vascular
Interventions
- DIAGNOSTIC_TEST
-
Protocol-defined Examinations
Lab tests (blood and urine and stool routine tests, hepatic and renal and thyroid function tests, tests for metabolic markers, tests for cardiac biomarkers, thrombosis-related tests, rheumatology tests, tests for inflammation markers), electrocardiography, echocardiography, Birmingham Vasculitis Activity Score (BVAS-3), 6-minute walk test, 1-minute squat test, vascular ultrasound, fibroblast activation protein inhibitor (FAPI) positron emission tomography/computed tomography (PET/CT), coronary angiography, optical coherence tomography (OCT), tests for exploratory biomarkers.
Sponsors & Collaborators
-
Peking Union Medical College Hospital
lead OTHER
Principal Investigators
-
Zhenyu Liu, M.D. · Peking Union Medical College Hospital
Eligibility
- Min Age
- 45 Years
- Max Age
- 64 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-11-02
- Primary Completion
- 2026-09-30
- Completion
- 2026-09-30
Countries
- China
Study Locations
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