MedDataX Logo

Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome

NCT06101862 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2300

Last updated 2025-02-19

No results posted yet for this study

Summary

Coronary computed tomography angiography (CCTA) is a widely accepted initial diagnostic test for individuals suspected of having chronic coronary syndromes. However, there is limited evidence supporting its use in the acute setting. So far, no large-scale randomized trial has examined the performance of CCTA as an alternative to invasive coronary angiography (ICA) in individuals with non-ST-segment elevation myocardial infarction (NSTEACS).

If CCTA were to replace ICA as a routine procedure for individuals with NSTEACS, it could reduce the risk of complications related to ICA, improve patient comfort, expedite decision-making, and reduce healthcare expenses and interhospital transfers.

Conditions

  • Ischemic Heart Disease
  • Non STEMI
  • Angina Pectoris, Unstable
  • Coronary Disease
  • Heart Attack
  • Acute Myocardial Infarction (AMI)
  • Randomized Controlled Trial
  • Diagnostic Imaging
  • Coronary Stenoses
  • Coronary Artery Disease
  • Multidetector Computed Tomography
  • Percutaneous Coronary Intervention

Interventions

PROCEDURE

CCTA

Participants will be examined with CCTA during admission.

PROCEDURE

Conventional ICA

Patients will be examined with conventional standard-of-care ICA.

OTHER

Team-based interventional triage

The CCTA will be discussed at a coronary CT-team conference to establish the treatment strategy and provide guidance for any necessary interventional procedure.

Sponsors & Collaborators

  • University of Copenhagen

    collaborator OTHER

  • Rigshospitalet, Denmark

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-01
Primary Completion
2026-10-01
Completion
2036-10-01

Countries

  • Denmark

Study Locations

Related Clinical Trials

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06101862 on ClinicalTrials.gov