A Study on the Outcome and Its Influencing Factors in Patients With Borderline Personality Disorder

NCT ID: NCT06005779

Last Updated: 2023-08-22

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 270 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-10-22
• Study Completion Date: 2024-09-30

Brief Summary

Borderline personality disorder (BPD) is a difficult chronic mental illness. This diagnosis is common in Western countries. Our researchers want to study the outcome and its influencing factors of BPD for the first time in China. Patients with BPD who had been hospitalized in Wuhan Mental Health Center were selected as the subjects. The researchers retrospectively collected the most recent hospitalization data of these patients, and then prospectively follow up them for 2 years to see how their condition will change. By analyzing all data, researchers hope to know deeply about the development law of this illness, and to provide evidence for releasing these patients' suffering.

Detailed Description

This study is an ambispective cohort study. The information collected in the retrospective part mainly included demographic data, comorbid psychiatric diagnosis, psychotherapeutive and pharmacotherapeutive data, times of hospitalization and patients' contact information. The above data were derived from electronic medical records. After informed consent, prospective follow-up was initiated primarily by telephone interviews and web-based questionnaires, or by in-person assessments at hospital return visits. Enrolled patients will be followed up at 6-month intervals after the first follow-up to assess psychiatric diagnosis, social function, and quality of life. The researchers are senior psychiatrists, all of whom received training on the use of questionnaires and inter-investigator consistency before the follow-up.

Cox Proportional Hazard Model is used to analyze the influencing factors of remission of BPD, and Generalized Estimating Equation Model is used to analyze the influencing factors of the patients' social function and quality of life.

Conditions

Borderline Personality Disorder

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: OTHER

Eligibility Criteria

Inclusion Criteria

• Diagnosis of BPD based on ICD-10 (F60.3)

Exclusion Criteria

• Comorbidity with severe physical disease
• Comorbidity with neurological diseases such as epilepsy
• Comorbidity with mental retardation

• Minimum Eligible Age: 12 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Wuhan Mental Health Centre

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Fan Yang, Master

Role: STUDY_DIRECTOR

Wuhan Mental Health Centre

Locations

Wuhan Mental Health Centre

Wuhan, Hubei, China

Countries

China

Other Identifiers

KY2018.77

Identifier Type: -

Identifier Source: org_study_id