Platelet and Red Blood Cell Volume Indices as Inflammatory Biomarkers in Ankylosing Spondylitis

NCT ID: NCT05997108

Last Updated: 2023-08-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-08-01

Study Completion Date

2024-02-01

Brief Summary

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this study aims to determine the relatioships among the NLR ,PLR ,MLR ,red cell volume and platelet volume indices levels as biomarkers in ankylosing spondylitis.

Detailed Description

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Conditions

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Ankylosing Spondylitis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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cases group

CBC

Intervention Type DIAGNOSTIC_TEST

Platelet and red blood cell volume indices

control group

CBC

Intervention Type DIAGNOSTIC_TEST

Platelet and red blood cell volume indices

Interventions

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CBC

Platelet and red blood cell volume indices

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* PATIENT WITH DISEASE DURATION OF MORE THAN 6 MONTHS
* AGE MORE THAN 18 YEARS

Exclusion Criteria

* PATIENT WITH CARDIAC ,CEREBROVASCULAR AND HEMATOLOGIC DIEASE
* PTIENT WITH HYPERTENSION ,DIABETES ,METABOLIS SYNDROMES AND OTHER AUTOIMMUNE RHEUMATIC DISEASES.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Margo Gerges Mofeed

Resident-rheumatology department-sohag general hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sohag university Hospital

Sohag, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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MARGO G MOFEED, resident

Role: CONTACT

01276496930

MOHAMMED A ESMAIL, assistant professor

Role: CONTACT

Facility Contacts

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Magdy M Amin, professor

Role: primary

References

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Azab B, Torbey E, Singh J, Akerman M, Khoueiry G, McGinn JT, Widmann WD, Lafferty J. Mean platelet volume/platelet count ratio as a predictor of long-term mortality after non-ST-elevation myocardial infarction. Platelets. 2011;22(8):557-66. doi: 10.3109/09537104.2011.584086. Epub 2011 Jun 30.

Reference Type BACKGROUND
PMID: 21714700 (View on PubMed)

Coutant F, Miossec P. Evolving concepts of the pathogenesis of rheumatoid arthritis with focus on the early and late stages. Curr Opin Rheumatol. 2020 Jan;32(1):57-63. doi: 10.1097/BOR.0000000000000664.

Reference Type BACKGROUND
PMID: 31644463 (View on PubMed)

Bekdas M, Goksugur SB, Sarac EG, Erkocoglu M, Demircioglu F. Neutrophil/lymphocyte and C-reactive protein/mean platelet volume ratios in differentiating between viral and bacterial pneumonias and diagnosing early complications in children. Saudi Med J. 2014 May;35(5):442-7.

Reference Type BACKGROUND
PMID: 24825803 (View on PubMed)

Kumano Y, Hasegawa Y, Kawahara T, Yasui M, Miyoshi Y, Matsubara N, Uemura H. Pretreatment Neutrophil to Lymphocyte Ratio (NLR) Predicts Prognosis for Castration Resistant Prostate Cancer Patients Underwent Enzalutamide. Biomed Res Int. 2019 Jan 20;2019:9450838. doi: 10.1155/2019/9450838. eCollection 2019.

Reference Type BACKGROUND
PMID: 30800682 (View on PubMed)

Other Identifiers

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Soh-Med-23-07-01MS

Identifier Type: -

Identifier Source: org_study_id

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