Mindfulness-Based Cognitive Therapy in Older People

NCT ID: NCT05995587

Last Updated: 2024-04-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

112 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-31

Study Completion Date

2023-11-30

Brief Summary

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Mindfulness-based interventions, such as mindfulness-based cognitive therapy (MBCT), have the potential in improving psychological health in older people. With the growing older people population, there is a need for greater social welfare capacity to promote their well-being. The project aims to:

1. Evaluate the effectiveness of MBCT in improving mental health and mindfulness in older people with depressive symptoms as compared to care as usual;
2. Compare the effectiveness between MBCT led by mindfulness teacher and that led by social workers;
3. Examine psychological flexibility as a potential mechanism of change in MBCT for depressive symptoms.

Detailed Description

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Depression is one of the most common yet under-recognized mental disorders in older adults in Hong Kong, and it is estimated that approximately one in 10 older people has clinically significant depression. With population aging, the number of older people with depression is slated to double in the next two decades, creating a substantial burden on the individuals, caregivers, and health care system. While pharmacological interventions are effective in reducing depression, medical risks can be complicated due to polypharmacy in older people. Non-pharmacological interventions may benefit the population by addressing the underlying dysfunctional cognitive processes associated with depression.

Mindfulness-based interventions, such as mindfulness-based cognitive therapy (MBCT), have the potential in improving psychological health in older people. MBCT is a group intervention originally designed to prevent recurrent depressive disorders. It combines mindfulness practices and cognitive-behavioural elements to enhance an individual's understanding of the interacting relationships among thoughts, emotions, bodily sensations, and behaviours. Mindfulness practice emphasizes on developing a moment-to-moment, non-judgmental awareness and may be helpful in alleviating depression by directing individual's attention to the present instead of ruminating in the past. Systematic reviews have shown the efficacy of MBCT in reducing depression, anxiety, loneliness, stress, sleep problems, ruminations, general mood, and positive affect. However, over half of the included studies lacked a control group and mixed findings were observed possibly because of inconsistent modifications to the protocol, methodological flaws, and study limitations.

The application of MBCT in the Chinese older population is understudied. Recently, a randomized controlled trial on MBCT for older people were conducted in Hong Kong. By comparing a standard MBCT to an active control group (physical exercise + health education) for older people with depression, it has been found that while both groups showed a reduction in the severity of depressive symptoms, only the MBCT group showed improvement in mindfulness.

With these promising findings, more studies are needed to establish the evidence base for the intervention and inform clinical practice in this population. The investigators aim to explore whether a modified MBCT based on older people's feedback can reduce depressive symptoms and improve mindfulness. With the growing older people population and thus a need for greater social welfare capacity to promote their well-being, the investigators will also examine whether a modified MBCT led by social workers under the supervision of a mindfulness teacher can benefit the population.

Conditions

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Depressive Symptoms

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Participants in the intervention group will either receive mindfulness training from a certified mindfulness teacher or from social workers (supervised by a certified mindfulness teacher). The care as usual group will receive usual service provided in District Elderly Community Centres (DECC) and Integrated Community Centre for Mental Wellness (ICCMW).
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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MBCT (mindfulness teacher)

Participants in the MBCT (mindfulness teacher) group will receive mindfulness training from a certified mindfulness teacher.

Group Type EXPERIMENTAL

Mindfulness-based cognitive therapy (MBCT)

Intervention Type BEHAVIORAL

MBCT combines mindfulness meditation with cognitive behavioural therapy (CBT) elements to reduce or prevent recurrent major depressive disorders.

MBCT (social workers)

Participants in the MBCT (social workers) group will receive mindfulness training from social workers (supervised by a certified mindfulness teacher).

Group Type EXPERIMENTAL

Mindfulness-based cognitive therapy (MBCT)

Intervention Type BEHAVIORAL

MBCT combines mindfulness meditation with cognitive behavioural therapy (CBT) elements to reduce or prevent recurrent major depressive disorders.

Care as usual group

The care as usual group will receive usual service provided in District Elderly Community Centres (DECC) and Integrated Community Centre for Mental Wellness (ICCMW).

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Mindfulness-based cognitive therapy (MBCT)

MBCT combines mindfulness meditation with cognitive behavioural therapy (CBT) elements to reduce or prevent recurrent major depressive disorders.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 60 years or older
* have depressive symptoms of mild level or above, as indicated by scoring 5 or more in PHQ-9
* can give informed consent to participate

Exclusion Criteria

* known history of autism, intellectual disability, schizophrenia-spectrum disorder, bipolar disorder, Parkinson's disease, or dementia
* imminent suicidal risk
* difficulty in communication
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Hong Kong Jockey Club Charities Trust

OTHER

Sponsor Role collaborator

Christian Family Service Centre

OTHER

Sponsor Role collaborator

The Mental Health Association of Hong Kong

OTHER

Sponsor Role collaborator

The Salvation Army, Hong Kong and Macau Command

OTHER

Sponsor Role collaborator

Caritas Medical Centre, Hong Kong

OTHER

Sponsor Role collaborator

Haven of Hope Hospital

OTHER

Sponsor Role collaborator

The University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Professor Terry Y.S. Lum

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Terry Lum, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Social Work and Social Administration, The University of Hong Kong

Gloria Wong, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Social Work and Social Administration, The University of Hong Kong

Locations

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Amity Place (Kwun Tong Central)

Kwun Tong, , Hong Kong

Site Status

Shun On District Elderly Community Centre (DECC)

Kwun Tong, , Hong Kong

Site Status

Haven of Hope District Elderly Community Service

Sai Kung, , Hong Kong

Site Status

Wellness Zone - Integrated Community Centre for Mental Wellness

Sai Kung, , Hong Kong

Site Status

Caritas Cheng Shing Fung District Elderly Centre (Sham Shui Po)

Sham Shui Po, , Hong Kong

Site Status

Tai Po Multi-service Centre for Senior Citizens

Tai Po, , Hong Kong

Site Status

Countries

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Hong Kong

References

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Geiger PJ, Boggero IA, Brake CA, Caldera CA, Combs HL, Peters JR, Baer RA. Mindfulness-Based Interventions for Older Adults: A Review of the Effects on Physical and Emotional Well-being. Mindfulness (N Y). 2016 Apr;7(2):296-307. doi: 10.1007/s12671-015-0444-1. Epub 2015 Sep 14.

Reference Type BACKGROUND
PMID: 27200109 (View on PubMed)

Hou J, Wong SY, Lo HH, Mak WW, Ma HS. Validation of a Chinese version of the Five Facet Mindfulness Questionnaire in Hong Kong and development of a short form. Assessment. 2014 Jun;21(3):363-71. doi: 10.1177/1073191113485121. Epub 2013 Apr 16.

Reference Type BACKGROUND
PMID: 23596271 (View on PubMed)

Ng SM. Validation of the 10-item Chinese perceived stress scale in elderly service workers: one-factor versus two-factor structure. BMC Psychol. 2013 Jun 19;1(1):9. doi: 10.1186/2050-7283-1-9. eCollection 2013.

Reference Type BACKGROUND
PMID: 25566361 (View on PubMed)

Shih VWY, Chan WC, Tai OK, Wong HL, Cheng CPW, Wong CSM. Mindfulness-Based Cognitive Therapy for Late-Life Depression: a Randomised Controlled Trial. East Asian Arch Psychiatry. 2021 Jun;31(2):27-35. doi: 10.12809/eaap2075.

Reference Type BACKGROUND
PMID: 34987115 (View on PubMed)

Sun WJ, Xu L, Chan WM, Lam TH, Schooling CM. Depressive symptoms and suicide in 56,000 older Chinese: a Hong Kong cohort study. Soc Psychiatry Psychiatr Epidemiol. 2012 Apr;47(4):505-14. doi: 10.1007/s00127-011-0362-z. Epub 2011 Mar 8.

Reference Type BACKGROUND
PMID: 21384121 (View on PubMed)

Tong X, An D, McGonigal A, Park SP, Zhou D. Validation of the Generalized Anxiety Disorder-7 (GAD-7) among Chinese people with epilepsy. Epilepsy Res. 2016 Feb;120:31-6. doi: 10.1016/j.eplepsyres.2015.11.019. Epub 2015 Nov 28.

Reference Type BACKGROUND
PMID: 26709880 (View on PubMed)

Wang W, Bian Q, Zhao Y, Li X, Wang W, Du J, Zhang G, Zhou Q, Zhao M. Reliability and validity of the Chinese version of the Patient Health Questionnaire (PHQ-9) in the general population. Gen Hosp Psychiatry. 2014 Sep-Oct;36(5):539-44. doi: 10.1016/j.genhosppsych.2014.05.021. Epub 2014 Jun 6.

Reference Type BACKGROUND
PMID: 25023953 (View on PubMed)

Thomas, R., Chur-Hansen, A. & Turner, M. A Systematic Review of Studies on the Use of Mindfulness-Based Cognitive Therapy for the Treatment of Anxiety and Depression in Older People. Mindfulness 11, 1599-1609 (2020). https://doi.org/10.1007/s12671-020-01336-3

Reference Type BACKGROUND

Morris, J. (2019). Development and validation of a short form of the Comprehensive assessment of Acceptance and Commitment Therapy processes (CompACT-SF). University of Nottingham.

Reference Type BACKGROUND

Segal, Z. V., Williams, J. M. G., & Teasdale, J. D. (2012). Mindfulness-based cognitive therapy for depression. Guilford Press.

Reference Type BACKGROUND

Wang YH, Wang YL, Leung DKY, Ng ZLY, Chan OLH, Wong SMY, Chan RCL, Liu T, Wong GHY, Lum TYS. Effectiveness of an age-modified mindfulness-based cognitive therapy (MBCT) in improving mental health in older people with depressive symptoms: a non-randomised controlled trial. BMC Complement Med Ther. 2025 Feb 26;25(1):81. doi: 10.1186/s12906-025-04781-6.

Reference Type DERIVED
PMID: 40011881 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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EA220105

Identifier Type: -

Identifier Source: org_study_id

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