Effects Of Caffeine On Cognitive Performance

NCT ID: NCT05995314

Last Updated: 2023-09-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-08-07

Study Completion Date

2023-09-04

Brief Summary

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Caffeine is a potent central nervous system stimulant that increases the activity in the prefrontal cortex and can improve cognitive skills. An improvement in these cognitive skills can lead to further benefits in athletic performance. Therefore, it is necessary to clarify the dose-response of caffeine on cognitive performance.The aim of this research will be to determine the effects of different doses of caffeine on sport-related cognitive aspects.

Detailed Description

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The investigators will require healthy, physically active young adults to complete three trials under the conditions: a) placebo, b) 3 mg/kg, or c) 6 mg/kg body mass of caffeine. In each trial, different cognitive abilities will be assessed using the following test batteries: reaction time (DynavisionTM D2), anticipation (Bassin Anticipation Timer), sustained attention (Go/No-Go and Eriksen Flanker Test) and memory tests. In addition, side effects and the perceived sensation index will be recorded 24 h after each test.

Conditions

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Caffeine

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors
To achieve the blinded placebo situation, a researcher not associated with the study will be performed the blinding and prepared identical capsules containing placebo or the corresponding dose of caffeine. This researcher will be assigned an alphanumeric code to each trial to blind participants and investigators

Study Groups

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PLACEBO

placebo (0 mg/kg of body mass of caffeine). The capsule will be filled with 3 mg/kg of body mass of cellulose.

Group Type PLACEBO_COMPARATOR

PLACEBO

Intervention Type DIETARY_SUPPLEMENT

3 mg/kg of cellulose (0 mg/kg of caffeine)

3mg/kg

3 mg/kg of body mass of caffeine (99% caffeine, Bulkpowders, United Kingdom).

Group Type EXPERIMENTAL

3 mg/kg of caffeine

Intervention Type DIETARY_SUPPLEMENT

Ingestion of 3 mg/kg of body mass of caffeine

6mg/kg

6 mg/kg of body mass of caffeine (99% caffeine, Bulkpowders, United Kingdom).

Group Type EXPERIMENTAL

6 mg/kg of caffeine

Intervention Type DIETARY_SUPPLEMENT

Ingestion of 6 mg/kg of body mass of caffeine

Interventions

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PLACEBO

3 mg/kg of cellulose (0 mg/kg of caffeine)

Intervention Type DIETARY_SUPPLEMENT

3 mg/kg of caffeine

Ingestion of 3 mg/kg of body mass of caffeine

Intervention Type DIETARY_SUPPLEMENT

6 mg/kg of caffeine

Ingestion of 6 mg/kg of body mass of caffeine

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Physically active individuals ( \>150 min/week moderate physical activity or \>75 min/week vigorous physical activity)
* Individuals without serious and undiagnosed health problems.

Exclusion Criteria

* Individuals with color blindness.
* Regular caffeine consumers (\>3 cups of coffee/day).
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Castilla-La Mancha

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Javier Abián-Vicén, PhD

Role: STUDY_DIRECTOR

University of Castilla-La Mancha

Locations

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Performance and Sport Rehabilitation Laboratory

Toledo, , Spain

Site Status

Countries

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Spain

References

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Ramirez-delaCruz M, Esteban-Garcia P, Abian P, Bravo-Sanchez A, Pinas-Bonilla I, Abian-Vicen J. Effects of different doses of caffeine on cognitive performance in healthy physically active individuals. Eur J Nutr. 2024 Dec;63(8):3025-3035. doi: 10.1007/s00394-024-03486-9. Epub 2024 Sep 4.

Reference Type DERIVED
PMID: 39231871 (View on PubMed)

Other Identifiers

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CAF_MR_2023

Identifier Type: -

Identifier Source: org_study_id

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