Effect of Atorvastatin as a Renal Protection in Patients With Systemic Inflammatory Response Syndrome Using Renal Arterial Resistive Index

NCT ID: NCT05946122

Last Updated: 2023-07-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1

Total Enrollment

106 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-30

Study Completion Date

2023-12-30

Brief Summary

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Offering renal protection in systemic inflammatory response syndrome by atorvastatin

Detailed Description

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Conditions

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Renal Protection

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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control group

Group Type PLACEBO_COMPARATOR

placebo drug

Intervention Type DRUG

tablet resembles atorvastatin

Active ( Ator) group

Group Type ACTIVE_COMPARATOR

Atorvastatin 40 Mg Oral Tablet

Intervention Type DRUG

oral atorvastatin for renal protection

Interventions

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Atorvastatin 40 Mg Oral Tablet

oral atorvastatin for renal protection

Intervention Type DRUG

placebo drug

tablet resembles atorvastatin

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients ( male and female) with systemic inflammatory response ( total leucocytic count \>12,000 mm3'. temperature \>38 C, Heart rate \>90 b/min and respiratory rate\>20 cycle).

Exclusion Criteria

* Hemodynamic instability
* Pre-admission chronic kidney disease.
* Intra-vascular coagulopathy
* Patients with myopathy.
Minimum Eligible Age

25 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Minia University

OTHER

Sponsor Role lead

Responsible Party

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Mina Maher

lecturer of anesthesia and pain medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Mina Maher Raouf

Minya, Minia University, Egypt

Site Status RECRUITING

Countries

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Egypt

Facility Contacts

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mina M raouf, MBBCH

Role: primary

02-01015752424

Other Identifiers

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343/ 8-2022

Identifier Type: -

Identifier Source: org_study_id

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